Evidence map›Paper›PMID 42198458›Full record

ReviewPharmaceuticals (Basel, Switzerland)2026

Guanidines: Privileged Scaffolds Against Neglected Tropical Diseases: A Review.

Luana Ribeiro Dos Anjos, Rodrigo Santos Aquino de Araújo, Malu Maria Lucas Dos Reis, Natalia C S Costa, Vitória Gaspar Bernardo, Eduardo Henrique Zampieri, Klinger Antonio da Franca Rodrigues, Eduardo Maffud Cilli, Eduardo René Pérez González, Francisco Jaime Bezerra Mendonça-Junior

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Luana Ribeiro Dos AnjosFine Organic Chemistry Laboratory School of Sciences and Technology, São Paulo State University (UNESP), Presidente Prudente 19060-080, São Paulo, Brazil.ORCID 0000-0002-2487-6176
Rodrigo Santos Aquino de AraújoFederal Institute of Education, Science, and Technology os Sertão Pernambucano (IFSertãoPE), Campus Santa Maria da Boa Vista, Santa Maria da Boa Vista 56380-000, Pernambuco, Brazil.ORCID 0000-0002-2403-8746
Malu Maria Lucas Dos ReisLaboratory of Synthesis and Drug Delivery, Department of Biological Sciences, State University of Paraíba, João Pessoa 58071-160, Paraíba, Brazil.ORCID 0000-0003-4480-680X
Natalia C S CostaDepartment of Biochemistry and Organic Chemistry, Institute of Chemistry, São Paulo State University (UNESP), Araraquara 14800-060, São Paulo, Brazil.ORCID 0000-0002-7250-4908
Vitória Gaspar BernardoLaboratory of Synthesis and Drug Delivery, Department of Biological Sciences, State University of Paraíba, João Pessoa 58071-160, Paraíba, Brazil.
Eduardo Henrique ZampieriFine Organic Chemistry Laboratory School of Sciences and Technology, São Paulo State University (UNESP), Presidente Prudente 19060-080, São Paulo, Brazil.ORCID 0000-0002-4547-693X
Klinger Antonio da Franca RodriguesInfectious Disease Laboratory-LADIC, Federal University of Parnaíba Delta-UFDPar, Campus Ministro Reis Velloso, São Benedito, Parnaíba 64202-020, Piauí, Brazil.ORCID 0000-0003-3904-3529
Eduardo Maffud CilliDepartment of Biochemistry and Organic Chemistry, Institute of Chemistry, São Paulo State University (UNESP), Araraquara 14800-060, São Paulo, Brazil.ORCID 0000-0002-4767-0904
Eduardo René Pérez GonzálezFine Organic Chemistry Laboratory School of Sciences and Technology, São Paulo State University (UNESP), Presidente Prudente 19060-080, São Paulo, Brazil.ORCID 0000-0003-1348-8554
Francisco Jaime Bezerra Mendonça-JuniorLaboratory of Synthesis and Drug Delivery, Department of Biological Sciences, State University of Paraíba, João Pessoa 58071-160, Paraíba, Brazil.ORCID 0000-0003-3588-833X

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 88887.177732/2025-00Coordenação de Aperfeicoamento de Pessoal de Nível Superior finance code 001Fundação de Apoio à Pesquisa do Estado da Paraíba 030/2023National Council for Scientific and Technological Development 316996/ 2023-8São Paulo Research Foundation 2021/02595-8São Paulo Research Foundation 2025/01056-7
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

antiparasitic compoundsdrug discoveryguanidine derivativesmedicinal chemistryneglected diseasesstructure–activity relationship

Identifiers

PMID42198458
PMCPMC13210131

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.