Evidence map›Paper›PMID 42198457›Full record

ReviewPharmaceuticals (Basel, Switzerland)2026

Gut Microbiota in Irritable Bowel Syndrome and Inflammatory Bowel Disease: Differences in Pathophysiology, Biomarkers, and Treatment Implications.

Ploutarchos Pastras, Ioanna Aggeletopoulou, Vasiliki Psalti, Christos Triantos

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ploutarchos PastrasDivision of Gastroenterology, Department of Internal Medicine, University of Patras, 26504 Patras, Greece.ORCID 0009-0001-7790-7845
Ioanna AggeletopoulouDivision of Gastroenterology, Department of Internal Medicine, University of Patras, 26504 Patras, Greece.ORCID 0000-0003-4489-1485
Vasiliki PsaltiDivision of Gastroenterology, Department of Internal Medicine, University of Patras, 26504 Patras, Greece.
Christos TriantosDivision of Gastroenterology, Department of Internal Medicine, University of Patras, 26504 Patras, Greece.ORCID 0000-0003-3094-8209

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alterations in the intestinal microbiota have been implicated in both irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). However, their biological significance and therapeutic implications differ substantially between the two conditions. Although dysbiosis is a common feature, the mechanisms by which alterations in the microbiota contribute to disease pathophysiology and clinical expression are distinct. Some pathways are more prominent in IBS (e.g., the gut-brain axis), whereas others are more prominent in IBD (e.g., reduced microbial diversity). Equally important are pathways that appear to play a role exclusively in IBD [e.g., Adherent-invasive

Indexed as

biomarkersinflammatory bowel diseaseinflammatory bowel syndromepathophysiologytreatment

Identifiers

PMID42198457
PMCPMC13210724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.