Evidence map›Paper›PMID 42198371›Full record

ReviewPharmaceuticals (Basel, Switzerland)2026

A Global Delphi Consensus on Acne and the Microbiome: Integrating International Expertise for Innovative Prevention and Therapeutic Strategies.

Marco Rocha, Leonel Fierro-Arias, Alison Layton, Vincenzo Bettoli, Ncoza Dlova, Eirini Merika, Thomas Dirschka, Pawinee Rerknimitr, Rakesh Newaj

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marco RochaDermatology Department, Universidade Federal de São Paulo, Sao Paulo 04023-062, Brazil.
Leonel Fierro-AriasHospital General de México, Mexico City 06720, Mexico.ORCID 0000-0001-6264-7342
Alison LaytonDermatology Department, University of York, York YO10 5DD, UK.ORCID 0000-0003-0473-3319
Vincenzo BettoliDermatology Department, University of Ferrara, 44121 Ferrara, Italy.
Ncoza DlovaDermatology Department, University of KwaZulu-Natal, Durban 4000, South Africa.
Eirini MerikaChelsea and Westminster Hospital NHS Foundation Trust, London SW10 9NH, UK.
Thomas DirschkaCentroDerm Clinic, Heinz-Fangman-Strasse 57, D-42287 Wuppertal, Germany.
Pawinee RerknimitrDermatology Department, Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0003-2051-5573
Rakesh NewajArwyp Medical Centre, Johannesburg 1619, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acne is a prevalent dermatological condition occurring globally and influenced by a variety of endogenous and exogenous factors. The microbiome and its contribution to skin disease have been increasingly explored, along with the influence of the exposome and host immune responses on this complex microbial system. Nine experts from different countries in Africa, America, Asia, and Europe gathered to harmonise definitions, identify key pathogenic and protective microbial strains, and prioritise the factors that most significantly impact the skin's microbiome in the context of acne. Opportunity areas on the role of the microbiome in the prevention, treatment, recurrence, and sequelae avoidance in acne were identified. The relationships between current treatments and the diversity of the microbiome were described. Current microbiome-targeted strategies were assessed, including practical considerations of innovative future perspectives. The panel discussions emphasise the urgent need for universally adaptable guidelines encompassing alternatives to oral antibiotic therapies, in light of increasing antimicrobial resistance and the significant burden of treatment-related adverse events.

Indexed as

acneglobal consensusmicrobiome

Identifiers

PMID42198371
PMCPMC13209985

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.