Evidence map›Paper›PMID 42198351›Full record

ArticlePharmaceuticals (Basel, Switzerland)2026

Therapeutic Potential of Ambroxol in Osteoarthritis: A Drug Repurposing Study.

Michelline Joana Tenório Albuquerque Madruga Mesquita, Anne Caroline Silva Nogueira da Cruz, Joana Tenório Albuquerque Madruga Mesquita Meireles Teixeira, Amanda Tissore Forwille Reis, Gustavo Medeiro Frota, Taciana Gabrielle Pinheiro de Moura Carvalho, Rafael Antônio Freire Carvalho, Jorge Antônio Meireles Teixeira, Marcelo Souza de Andrade, Rafael Cardoso Carvalho and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Michelline Joana Tenório Albuquerque Madruga MesquitaPost-Graduate Program in Health Sciences (UFMA), Medicine Departament I, Federal University of Maranhao (UFMA), Sao Luis 65080-805, MA, Brazil.ORCID 0000-0002-4133-7123
Anne Caroline Silva Nogueira da CruzPost-Graduate Program in Health Sciences, Federal University of Maranhao (UFMA), Sao Luis 65080-805, MA, Brazil.
Joana Tenório Albuquerque Madruga Mesquita Meireles TeixeiraMedical School, University CEUMA, Sao Luis 65075-120, MA, Brazil.
Amanda Tissore Forwille ReisCollege of Pharmacy, Federal University of Maranhao (UFMA), Sao Luis 65080-805, MA, Brazil.ORCID 0000-0002-9442-874X
Gustavo Medeiro FrotaGraduate Program in Biotechnology-RENORBIO, Federal University of Maranhao (UFMA), Sao Luis 65080-805, MA, Brazil.ORCID 0000-0001-7496-9699
Taciana Gabrielle Pinheiro de Moura CarvalhoMedicine Department I, Federal University of Maranhao (UFMA), Sao Luis 65080-805, MA, Brazil.
Rafael Antônio Freire CarvalhoMedical School, Pinheiro Campus, Federal University of Maranhao (UFMA), Pinheiro 65200-000, MA, Brazil.ORCID 0009-0009-1106-9517
Jorge Antônio Meireles TeixeiraMedicine Department I, Federal University of Maranhao (UFMA), Sao Luis 65080-805, MA, Brazil.
Marcelo Souza de AndradeLaboratory of Molecular Biology (Labiomol), Post Graduation Program in Adult Health (PPGSAD), Federal University of Maranhao (UFMA), Sao Luis 65080-805, MA, Brazil.ORCID 0000-0002-8518-6910
Rafael Cardoso CarvalhoSpecial Coordination in Biological and Health Sciences I, Center for Biological and Health Sciences (CCBS) Federal University of Maranhao (UFMA), Sao Luis 65080-805, MA, Brazil.ORCID 0000-0001-7073-8308
Eduardo Martins de SousaGraduate Program in Applied Biosciences to Health, University CEUMA, Sao Luis 65075-120, MA, Brazil.ORCID 0000-0002-2506-169X
Joicy Cortez de Sá SousaSpecial Coordination of Morphology (CEMOR/CCBS/UFMA), Graduate Program in Health Sciences-PPGCS, Federal University of Maranhao (UFMA), Sao Luis 65080-805, MA, Brazil.
Sebastião Vieira de MoraisMedicine Department II, Federal University of Maranhao (UFMA), Sao Luis 65080-805, MA, Brazil.
Eduardo Rodrigues SilvaGraduate Program in Biotechnology-RENORBIO, Federal University of Maranhao (UFMA), Sao Luis 65080-805, MA, Brazil.ORCID 0009-0000-3371-1413
Maria do Socorro de Sousa CartágenesPhysiological Sciences Department, Federal University of Maranhao (UFMA), Sao Luis 65080-805, MA, Brazil.
João Batista Santos GarciaMedicine Department II, Federal University of Maranhao (UFMA), Sao Luis 65080-805, MA, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ambroxolchronic paindrug repurposingexperimental osteoarthritisinflammation

Identifiers

PMID42198351
PMCPMC13209346

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.