Evidence map›Paper›PMID 42198125›Full record

ArticlePolymers2026

Engineering Porous PET-RAFT Scaffolds with PLGA-Insulin Nanoparticles: Advancing Bone Tissue Regeneration Through Additive Manufacturing.

Fernando E Rodríguez-Umanzor, Mauricio A Sarabia-Vallejos, Nicolás F Acuña-Ruiz, Scarleth A Romero-De la Fuente, Nicolás A Cohn-Inostroza, David Ortiz Puerta, Enrique Martínez-Campos, Juan Rodríguez-Hernández, Claudio A Terraza Inostroza, Carmen M González-Henríquez

Abstract read
In one paragraph

Article in Polymers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fernando E Rodríguez-UmanzorDepartamento de Química, Facultad de Ciencias Naturales, Matemáticas y del Medio Ambiente, Universidad Tecnológica Metropolitana, Santiago 7800003, Chile.ORCID 0000-0002-7036-4665
Mauricio A Sarabia-VallejosFacultad de Ingeniería, Universidad San Sebastián, Santiago 8420524, Chile.
Nicolás F Acuña-RuizDepartamento de Química, Facultad de Ciencias Naturales, Matemáticas y del Medio Ambiente, Universidad Tecnológica Metropolitana, Santiago 7800003, Chile.
Scarleth A Romero-De la FuentePrograma PhD en Ciencia de Materiales e Ingeniería de Procesos, Universidad Tecnológica Metropolitana, Santiago 8940000, Chile.ORCID 0009-0000-2609-8323
Nicolás A Cohn-InostrozaDepartamento de Química, Facultad de Ciencias Naturales, Matemáticas y del Medio Ambiente, Universidad Tecnológica Metropolitana, Santiago 7800003, Chile.ORCID 0000-0002-8701-7037
David Ortiz PuertaBiomedical Engineering School, Faculty of Engineering, Universidad de Valparaíso, Valparaíso 2362905, Chile.ORCID 0000-0001-6285-3066
Enrique Martínez-CamposGroup of Organic Synthesis and Bioevaluation, Instituto Pluridisciplinar, Universidad Complutense de Madrid, Associated Unit to the ICTP-IQM-CSIC, 28040 Madrid, Spain.ORCID 0000-0002-7110-3651
Juan Rodríguez-HernándezPolymer Functionalization Group, Departamento de Química Macromolecular Aplicada, Instituto de Ciencia y Tecnología de Polímeros-Consejo Superior de Investigaciones Científicas (ICTP-CSIC), 28006 Madrid, Spain.
Claudio A Terraza InostrozaResearch Laboratory for Organic Polymers (RLOP), Faculty of Chemistry and Pharmacy, Pontificia Universidad Católica de Chile, Santiago 7820436, Chile.ORCID 0000-0002-6326-8771
Carmen M González-HenríquezDepartamento de Química, Facultad de Ciencias Naturales, Matemáticas y del Medio Ambiente, Universidad Tecnológica Metropolitana, Santiago 7800003, Chile.ORCID 0000-0001-9058-5425

Funding

Agencia Nacional de Investigación y Desarrollo 21230964Fondo de Fomento al Desarrollo Científico y Tecnológico ID23I10110Fondo Nacional de Desarrollo Científico y Tecnológico 11230427Fondo Nacional de Desarrollo Científico y Tecnológico 1220251Fondo Nacional de Desarrollo Científico y Tecnológico 1260671Fondo Nacional de Desarrollo Científico y Tecnológico 1260875
6 · The paper itself

Abstract

Multifunctional scaffolds that combine structural support with the controlled delivery of bioactive agents remain a major challenge in tissue engineering. To extend the use of these devices in biomedicine, 3D printing is presented as an alternative that enables the manufacture of complex devices tailored to each patient, thereby solving specific problems in a timely and efficient manner. In this study, porous 3D scaffolds were fabricated via digital light processing (DLP) using a PET-RAFT resin composed of 2-(dimethylamino)ethyl methacrylate (DMAEMA) and poly(ethylene glycol) diacrylate (PEGDA

Indexed as

3D printingbone tissue engineeringPET-RAFT resinPLGA–Insulin nanoparticlesporous scaffolds

Identifiers

PMID42198125
PMCPMC13211159

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.