Evidence map›Paper›PMID 42197534›Full record

ArticleMicroorganisms2026

Salmonella Effector SpvC Targets SEC23B of Intestinal Epithelial Cells to Resist Gasdermin D-Mediated Protection Against Systemic Infection.

Liting Zhou, Yan Yang, Li Kang, Jiayi You, Ye Wang, Ailing Xu, Guangmin Tu, Rui Huang, Zhengyu Zhou, Minghui Li and 1 more

Abstract read
In one paragraph

Article in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Liting ZhouSchool of Basic Medical Science, Suzhou Medical College of Soochow University, Suzhou 215123, China.
Yan YangSchool of Basic Medical Science, Suzhou Medical College of Soochow University, Suzhou 215123, China.
Li KangSchool of Basic Medical Science, Suzhou Medical College of Soochow University, Suzhou 215123, China.
Jiayi YouSchool of Basic Medical Science, Suzhou Medical College of Soochow University, Suzhou 215123, China.
Ye WangSchool of Basic Medical Science, Suzhou Medical College of Soochow University, Suzhou 215123, China.
Ailing XuSchool of Basic Medical Science, Suzhou Medical College of Soochow University, Suzhou 215123, China.
Guangmin TuSchool of Basic Medical Science, Suzhou Medical College of Soochow University, Suzhou 215123, China.
Rui HuangSchool of Basic Medical Science, Suzhou Medical College of Soochow University, Suzhou 215123, China.
Zhengyu ZhouLaboratory Animal Center, Suzhou Medical College of Soochow University, Suzhou 215123, China.ORCID 0000-0001-5712-9495
Minghui LiSchool of Basic Medical Science, Suzhou Medical College of Soochow University, Suzhou 215123, China.ORCID 0000-0002-7657-6589
Shuyan WuSchool of Basic Medical Science, Suzhou Medical College of Soochow University, Suzhou 215123, China.

Funding

Basic Research Program of Jiangsu BK20250440National Natural Science Foundation of China 31970132National Natural Science Foundation of China 31970505National Natural Science Foundation of China 32070665National Natural Science Foundation of China 32270187Suzhou Industrial Park Healthcare Talent Support Initiative 2024(30)
6 · The paper itself

Abstract

Salmonella infects a wide range of hosts, causing gastroenteritis or systemic infection in humans and animals, highlighting the urgent need for a deeper understanding of its pathogenesis. SpvC, a critical virulence determinant of salmonella, facilitates bacterial dissemination. Gasdermin D (GSDMD) is the only gasdermin known to protect mice against acute

Indexed as

GSDMDintestinal epithelial barriersalmonella effector SpvCSEC23B

Identifiers

PMID42197534
PMCPMC13209872

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.