Evidence map›Paper›PMID 42197230›Full record

ArticleMolecules (Basel, Switzerland)2026

Novel Aloe-Emodin Derivatives as Potential Anticancer Agents: Synthesis, Characterization and Cytotoxic Activity.

Jeltzlin Semerel, Shuhe Zheng, Haoyue Hu, Yuyu Fang, Nigel John, Pedro Fardim, Wim Dehaen

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jeltzlin SemerelSISSTEM Program, Faculty of Arts and Science, University of Aruba, J. Irausquinplein 4, Oranjestad, Aruba.ORCID 0000-0001-9332-3818
Shuhe ZhengInstitut de Science et D'ingénierie Supramoléculaires, University of Strasbourg, 8 Allée Gaspard Monge, 67000 Strasbourg, France.ORCID 0009-0004-4384-8367
Haoyue HuSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Yuyu FangSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Nigel JohnSISSTEM Program, Faculty of Arts and Science, University of Aruba, J. Irausquinplein 4, Oranjestad, Aruba.
Pedro FardimDepartment of Chemical Engineering, KU Leuven, Celestijnenlaan 200F, B-3001 Leuven, Belgium.
Wim DehaenDepartment of Chemistry, KU Leuven, Celestijnenlaan 200F, B-3001 Leuven, Belgium.ORCID 0000-0002-9597-0629

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The fusion of heterocycles onto an anthraquinone scaffold represents a promising strategy to optimize anticancer activity. This study has the aim to synthesize and characterize novel anthra[1,2-

Indexed as

AnthraquinonesAntineoplastic AgentsCell Line, TumorCell ProliferationDrug Screening Assays, AntitumorHumansMCF-7 CellsMolecular StructureStructure-Activity Relationshipaloe emodinAnthraquinonesAntineoplastic Agentsaloe-emodinanthra[1,2-b]furanCastro–Stephens couplingcytotoxic activity

Identifiers

PMID42197230
PMCPMC13210113

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.