Evidence map›Paper›PMID 42197227›Full record

ArticleMolecules (Basel, Switzerland)2026

Citrus Peel Flours: From Residues to Bioactive Ingredients for Food Applications.

Daniele Sales, Tiane C Finimundy, Jessica Ribeiro, Sandrina Heleno, Filipa Mandim, Marina Kostić, Marina Soković, Lillian Barros, Cristina Caleja, Eliana Pereira

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Daniele SalesCIMO, LA SusTEC, Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.
Tiane C FinimundyCIMO, LA SusTEC, Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.ORCID 0000-0003-3516-0795
Jessica RibeiroCIMO, LA SusTEC, Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.ORCID 0000-0001-8274-2013
Sandrina HelenoCIMO, LA SusTEC, Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.ORCID 0000-0001-7224-1098
Filipa MandimCIMO, LA SusTEC, Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.ORCID 0000-0002-6494-2326
Marina KostićInstitute for Biological Research "Siniša Stanković"-National Institute of the Republic of Serbia, University of Belgrade, Bulevar despota Stefana 142, 11108 Belgrade, Serbia.ORCID 0000-0001-8717-6495
Marina SokovićInstitute for Biological Research "Siniša Stanković"-National Institute of the Republic of Serbia, University of Belgrade, Bulevar despota Stefana 142, 11108 Belgrade, Serbia.ORCID 0000-0002-7381-756X
Lillian BarrosCIMO, LA SusTEC, Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.ORCID 0000-0002-9050-5189
Cristina CalejaCIMO, LA SusTEC, Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.ORCID 0000-0002-5769-8484
Eliana PereiraCIMO, LA SusTEC, Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.ORCID 0000-0003-2854-6745

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The high consumption of citrus fruits generates large amounts of peel bioresidues, whose valorization represents an important strategy for sustainable agri-food systems. This study aimed to characterize the nutritional, chemical, and bioactive properties of flours obtained from orange (FL), tangerine (FT), lime (FLA), and lemon (FLO) peels, and to evaluate their potential as functional food ingredients. The flours were evaluated for proximate composition, organic acids, phenolic compounds, fatty acids, free sugars, and bioactive properties. Lime flour showed the highest protein, ash, dietary fiber, and total phenolic contents, with hesperidin identified as the predominant compound. The corresponding extracts exhibited relevant antioxidant, antimicrobial, antiproliferative, and nitric oxide (NO) production inhibitory activities, with lime flour presenting the strongest overall bioactive potential. Based on these results, lime flour was selected for application in a food model by partially replacing wheat flour (10% and 20%) in "Madalenas", a traditional Portuguese muffin cake. The incorporation of lime flour improved product preservation compared with the control formulation and samples containing a synthetic preservative (potassium sorbate). These findings highlight the potential of citrus peel flours, particularly lime flour, as natural functional ingredients and sustainable alternatives for food formulations, contributing to waste valorization and circular economy approaches in the agri-food sector.

Indexed as

CitrusFlourFruitAnti-Infective AgentsAntioxidantsDietary FiberPhenolsPlant ExtractsAnti-Infective AgentsAntioxidantsDietary FiberPhenolsPlant Extractsbioactivitycircular economycitrus residuesfood applicationsfunctional ingredients

Identifiers

PMID42197227
PMCPMC13209230

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.