Evidence map›Paper›PMID 42197025›Full record

ArticleNutrients2026

Red Blood Cell Parameters, Iron Metabolism and Vitamin B12 Status in Children with Obesity: Associations with Diet and Obesity-Related Complications.

Ewelina Cichocka-Mroczek, Anna Iwańska, Dawid Goncerz, Dorota Łukasik, Aleksandra Molek, Małgorzata Wójcik, Agnieszka Kozioł-Kozakowska

Abstract read
In one paragraph

Article in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ewelina Cichocka-MroczekLaboratory of Pediatric Dietetics, Department of Pediatrics, Gastroenterology and Nutrition, Jagiellonian University Medical College, 30-663 Cracow, Poland.ORCID 0009-0003-2848-6903
Anna IwańskaDoctoral School of Medical and Health Sciences, Jagiellonian University Medical College, 30-663 Cracow, Poland.
Dawid GoncerzDoctoral School of Medical and Health Sciences, Jagiellonian University Medical College, 30-663 Cracow, Poland.
Dorota ŁukasikStudents' Scientific Group, Department of Paediatric and Adolescents Endocrinology, Chair of Paediatrics, Paediatric Institute, Jagiellonian University Medical College, 30-663 Cracow, Poland.
Aleksandra MolekStudents' Scientific Group, Department of Paediatric and Adolescents Endocrinology, Chair of Paediatrics, Paediatric Institute, Jagiellonian University Medical College, 30-663 Cracow, Poland.ORCID 0009-0009-2226-0392
Małgorzata WójcikDepartment of Pediatric and Adolescent Endocrinology, Chair of Pediatrics, Pediatric Institute, Jagiellonian University, 30-663 Cracow, Poland.ORCID 0000-0003-3889-1913
Agnieszka Kozioł-KozakowskaLaboratory of Pediatric Dietetics, Department of Pediatrics, Gastroenterology and Nutrition, Jagiellonian University Medical College, 30-663 Cracow, Poland.ORCID 0000-0003-4770-5641

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo assess abnormalities in red blood cell parameters, iron metabolism, and vitamin B12 status in children with obesity, and to evaluate the influence of dietary intake and obesity-related complications on these variables.

methodsA retrospective analysis was conducted in 152 children with obesity. Anthropometric, biochemical, and hematological parameters were assessed. Dietary intake was evaluated in a subgroup of 33 participants using 3-day food records.

resultsNo cases of low hemoglobin levels were identified. However, elevated TIBC and occasional low ferritin levels suggested disturbances in iron metabolism. BMI Z-score was positively associated with red blood cell count and selected iron metabolism markers, whereas higher body fat percentage was negatively associated with hemoglobin and hematocrit. Dietary analysis indicated that protein and vitamin B12 intake were associated with erythrocyte parameters, while no associations were found for iron or folate intake. Elevated liver enzymes were associated with higher hemoglobin, hematocrit, and MCV values.

conclusionsPediatric obesity was not associated with low hemoglobin levels but may be linked to early, subclinical disturbances in iron metabolism. These findings should be confirmed using more comprehensive biomarkers. Dietary factors, particularly vitamin B12 intake, may contribute to variability in erythrocyte parameters; however, these associations should be interpreted with caution. The observed relationship between liver function and erythrocyte indices warrants further investigation.

Indexed as

DietErythrocytesIronPediatric ObesityVitamin B 12AdolescentBiomarkersBody Mass IndexChildErythrocyte IndicesFemaleFerritinsHemoglobinsHumansMaleNutritional StatusBiomarkersFerritinsHemoglobinsIronVitamin B 12adipositybody compositionchildhood obesitydietary intakeerythrocyte parametersferritiniron statuspediatric populationtotal iron-binding capacityvitamin B12

Identifiers

PMID42197025
PMCPMC13209332

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.