Evidence map›Paper›PMID 42196973›Full record

Trial reportNutrients2026

Differential Time-of-Day Effects of Caffeine Capsule and Mouth Rinse on Physical Performance and Volleyball-Specific Skills in Adolescent Male Volleyball Players.

Salma Belhaj Amor, Wissem Dhahbi, Marouen Souaifi, Halil İbrahim Ceylan, Johnny Padulo, Stefano Vando, Nagihan Burçak Ceylan, Raul Ioan Muntean, Nizar Souissi

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Salma Belhaj AmorPhysical Activity, Sport and Health Research Unit (UR18JS01), National Observatory of Sports, Tunis 1003, Tunisia.
Wissem DhahbiResearch Unit (UR22JS01) "Sport Sciences, Health and Movement", High Institute of Sport and Physical Education of Kef, University of Jendouba, El Kef 7100, Tunisia.ORCID 0000-0001-6221-546X
Marouen SouaifiResearch Unit (UR22JS01) "Sport Sciences, Health and Movement", High Institute of Sport and Physical Education of Kef, University of Jendouba, El Kef 7100, Tunisia.ORCID 0009-0002-3387-9886
Halil İbrahim CeylanPhysical Education of Sports Teaching Department, Faculty of Sports Sciences, Atatürk University, 25240 Erzurum, Türkiye.ORCID 0009-0005-2214-4667
Johnny PaduloDepartment of Biomedical Sciences for Health (SCIBIS), Università Degli Studi di Milano, 20134 Milan, Italy.ORCID 0000-0002-4254-3105
Stefano VandoFitkion-Center for Kinesiology and Adapted Physical Activity, 04100 Latina, Italy.ORCID 0000-0001-7302-4191
Nagihan Burçak CeylanGraduate Education Institute, Bayburt University, 69000 Bayburt, Türkiye.
Raul Ioan MunteanDepartment of Physical Education and Sport, Faculty of Law and Social Sciences, University "1 Decembrie 1918" of Alba Iulia, 510009 Alba Iulia, Romania.ORCID 0000-0003-4615-6687
Nizar SouissiPhysical Activity, Sport and Health Research Unit (UR18JS01), National Observatory of Sports, Tunis 1003, Tunisia.ORCID 0000-0003-1227-8221

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study compared the acute effects of caffeine capsule ingestion and caffeine mouth rinsing on physical performance and volleyball-specific skills at different times of day in trained adolescent male volleyball players.

methodsTwenty-four well-trained male volleyball players (age: 16.9 ± 0.7 years) completed a randomized, double-blind, placebo-controlled crossover study involving three supplementation conditions, caffeine capsule (CAFcap, 3 mg·kg

resultsSignificant main effects of condition and time of day were observed for all outcomes. Significant condition × time-of-day interactions were found for SJ, CMJ, attack jump, and change-of-direction speed, indicating that caffeine-related ergogenic effects were most evident in the morning and at midday, whereas these benefits were attenuated in the evening when baseline performance was highest. At 08:00 and 12:00, both CAFcap and CAFrinse improved jump performance and agility compared with PLA, with capsule ingestion showing a small-to-moderate advantage over mouth rinsing for selected lower-limb power outcomes at midday (mean difference range: 0.51-0.57 cm; dz = 0.57-0.65). For block jump, spike accuracy, and serve accuracy, both caffeine conditions improved performance relative to placebo, while a progressive improvement across the day was observed under all conditions, including placebo, confirming a diurnal rhythm effect independent of supplementation. Overall, the data indicate that caffeine partially reduced the amplitude of diurnal variation in several physical performance measures.

conclusionsBoth caffeine capsule ingestion and caffeine mouth rinsing enhanced physical and volleyball-specific performance in trained adolescent male volleyball players. The ergogenic effects were more pronounced earlier in the day, suggesting that caffeine may be particularly useful for attenuating morning and midday performance decrements, while mouth rinsing represents a practical non-ingestive alternative with meaningful efficacy.

Indexed as

Athletic PerformanceCaffeineMouthwashesVolleyballAdolescentCapsulesCross-Over StudiesDouble-Blind MethodHumansMaleTime FactorsCaffeineCapsulesMouthwashesadolescent athletescaffeinechange-of-direction speedjump performancemouth rinseskill accuracytime of dayvolleyball

Identifiers

PMID42196973
PMCPMC13209374

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.