Evidence map›Paper›PMID 42196838›Full record

ArticleDiagnostics (Basel, Switzerland)2026

Is "Physiological Lysis" in Viscoelastometry a Plasmin-Mediated Process?

Anikó Smudla, Herbert Schöchl, Andreas Calatzis, Csikós Richárd Gergely, János Fazakas

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anikó SmudlaDepartment of Intensive Therapy, Semmelweis University, 1082 Budapest, Hungary.
Herbert SchöchlLudwig-Boltzmann-Institute for Traumatology, The Research Centre in Cooperation with AUVA, 1200 Vienna, Austria.ORCID 0000-0001-6028-1551
Andreas CalatzisInstitute for Cardiovascular Prevention, LMU Munich University Hospital, 80336 Munich, Germany.
Csikós Richárd GergelyHeart and Vascular Center, Semmelweis University, 1122 Budapest, Hungary.ORCID 0000-0002-3161-1272
János FazakasDepartment of Intensive Therapy, Semmelweis University, 1082 Budapest, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viscoelastic testing (VET) is widely used to guide hemostatic therapy in patients with coagulopathy. One important application is the detection of fibrinolysis, defined as a reduction in clot amplitude after maximum clot firmness (MCF), quantified as maximum lysis (ML). Low ML values have recently been associated with adverse outcomes in trauma and sepsis. However, the biological basis of low ML remains unclear.

Indexed as

clot retractionmaximum lysisphysiologic lysistranexamic acidviscoelastometry

Identifiers

PMID42196838
PMCPMC13205181

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.