Evidence map›Paper›PMID 42196560›Full record

ArticleInternational journal of molecular sciences2026

The Effect of 2.45 GHz Radiofrequency Electromagnetic Radiation on Components of the Hypothalamic-Pituitary-Gonadal Axis in Male Rats.

Sivasatyan Vijay, Siti Fatimah Ibrahim, Khairul Osman, Aini Farzana Zulkefli, Mohd Farisyam Mat Ros, Norazurashima Jamaludin, Syed Muhamad Asyraf Syed Taha, Atikah Hairulazam, Farah Hanan Fathihah Jaffar

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sivasatyan VijayDepartment of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia (UKM), Cheras, Kuala Lumpur 56000, Malaysia.
Siti Fatimah IbrahimDepartment of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia (UKM), Cheras, Kuala Lumpur 56000, Malaysia.ORCID 0000-0002-4474-8032
Khairul OsmanForensic Science Program, Center for Diagnostics, Therapeutics, and Investigative Studies (CODTIS), Faculty of Health Sciences, Universiti Kebangsaan Malaysia (UKM), Jalan Raja Muda Abdul Aziz, Kuala Lumpur 50300, Malaysia.ORCID 0000-0003-3348-0672
Aini Farzana ZulkefliDepartment of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia (UKM), Cheras, Kuala Lumpur 56000, Malaysia.
Mohd Farisyam Mat RosDepartment of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia (UKM), Cheras, Kuala Lumpur 56000, Malaysia.
Norazurashima JamaludinForensic Science Program, Center for Diagnostics, Therapeutics, and Investigative Studies (CODTIS), Faculty of Health Sciences, Universiti Kebangsaan Malaysia (UKM), Jalan Raja Muda Abdul Aziz, Kuala Lumpur 50300, Malaysia.ORCID 0009-0001-1835-1939
Syed Muhamad Asyraf Syed TahaDepartment of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia (UKM), Cheras, Kuala Lumpur 56000, Malaysia.ORCID 0009-0005-8931-5897
Atikah HairulazamDepartment of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia (UKM), Cheras, Kuala Lumpur 56000, Malaysia.
Farah Hanan Fathihah JaffarDepartment of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia (UKM), Cheras, Kuala Lumpur 56000, Malaysia.ORCID 0000-0001-7645-3805

Funding

Universiti Kebangsaan Malaysia GGPM-2022-031
6 · The paper itself

Abstract

The brain and testes are connected via the hypothalamic-pituitary-gonadal (HPG) axis. Both are vulnerable to radiofrequency electromagnetic radiation (RF-EMR). However, no comprehensive study had evaluated the effects of RF-EMR on key hormones along this axis. Hereby, this study evaluated the effect of RF-EMR on the hormonal changes along the axis, including the neuropeptide kisspeptin. A total of 18 (N = 18) adult Sprague-Dawley rats were divided into three groups (n = 6): Control, 4 h, and 24 h. The Control group was sham-exposed to an inactive router. The exposed groups were subjected to 2.45 GHz RF-EMR for 4 and 24 h daily, for 60 days at a 20 cm distance. The power density was 0.141 W/m

Indexed as

Electromagnetic RadiationHypothalamic-Pituitary-Gonadal AxisHypothalamo-Hypophyseal SystemRadio WavesTestisAnimalsFollicle Stimulating HormoneGonadotropin-Releasing HormoneHypothalamusKisspeptinsLuteinizing HormoneMaleRatsRats, Sprague-DawleyTestosteroneFollicle Stimulating HormoneGonadotropin-Releasing HormoneKiss1 protein, ratKisspeptinsLuteinizing HormoneTestosteroneFSHGnRHkisspeptinLHRF-EMRtestosterone

Identifiers

PMID42196560
PMCPMC13207925

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.