Evidence map›Paper›PMID 42196306›Full record

ArticleInternational journal of molecular sciences2026

APOE4 Alters Early Transcriptional Programs and Inflammatory Signaling in Human Induced Pluripotent Stem Cells.

Wiebke Schulten, Nele Johanne Czaniera, Mehran Fazel, Barbara Kaltschmidt, Christian Kaltschmidt

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wiebke SchultenDepartment of Cell Biology, University of Bielefeld, 33615 Bielefeld, Germany.
Nele Johanne CzanieraDepartment of Cell Biology, University of Bielefeld, 33615 Bielefeld, Germany.
Mehran FazelDepartment of Cell Biology, University of Bielefeld, 33615 Bielefeld, Germany.
Barbara KaltschmidtForschungsverbund BioMedizin Bielefeld, Ostwestfalen-Lippe (OWL) (FBMB E.V.), 33617 Bielefeld, Germany.
Christian KaltschmidtDepartment of Cell Biology, University of Bielefeld, 33615 Bielefeld, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The

Indexed as

Apolipoprotein E4Induced Pluripotent Stem CellsInflammationSignal TransductionTranscription, GeneticAlzheimer DiseaseApolipoprotein E3Cell DifferentiationGene Expression RegulationGenotypeHumansProtein Interaction MapsSOXB1 Transcription FactorsApolipoprotein E3Apolipoprotein E4SOXB1 Transcription FactorsAlzheimer’s diseaseAPOE4differentiationEGRiPSCsmetallothioneinneurodevelopmentRNA sequencingTNFR

Identifiers

PMID42196306
PMCPMC13207287

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.