ArticleInternational journal of molecular sciences2026
Type-1 Ryanodine Receptor Plays an Important Role in Cardiac Hypertrophy and Heart Failure by Increasing Type-2 Ryanodine Receptor-Mediated Calcium Release.
Yong-Xiao Wang, Ed Wilson Santos, Sarahann Mistretta, Yuexing Yuan, Harold A Singer, Shey-Shing Sheu, Yun-Min Zheng
Abstract read
In one paragraphArticle in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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1 · What the graph read from itWhat it found
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2 · The registryThe trial behind it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
7 authors.
Yong-Xiao WangDepartment of Molecular and Cellular Physiology, Albany Medical College, Albany, NY 12208, USA.ORCID 0000-0002-2674-7116 Ed Wilson SantosDepartment of Molecular and Cellular Physiology, Albany Medical College, Albany, NY 12208, USA.ORCID 0000-0002-7736-9645 Sarahann MistrettaDepartment of Molecular and Cellular Physiology, Albany Medical College, Albany, NY 12208, USA.
Yuexing YuanCenter for Translational Medicine, Department of Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Harold A SingerDepartment of Molecular and Cellular Physiology, Albany Medical College, Albany, NY 12208, USA.
Shey-Shing SheuCenter for Translational Medicine, Department of Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA.ORCID 0000-0003-3838-3601 Yun-Min ZhengDepartment of Molecular and Cellular Physiology, Albany Medical College, Albany, NY 12208, USA.
Funding
Novel signaling in chronic hypoxic responses in pulmonary arteriesR01HL122865 · NHLBI · ALBANY MEDICAL COLLEGE · PI WANG, YONG-XIAO · 2015 to 2018
$1.9MCerebral vascular calcium signaling in diabetic Alzheimer's disease-related dementiasR03AG070784 · NIA · ALBANY MEDICAL COLLEGE · PI WANG, YONG-XIAO · 2021 to 2021
$326kInternational Heart and Lung Institute R01HL108232NHLBI NIH HHS R01HL122865NIA NIH HHS R03AG070784
6 · The paper itselfAbstract
Type-1 ryanodine receptor (RyR1) is essential for skeletal muscle contraction. This Ca
Indexed as
CalciumCardiomegalyHeart FailureRyanodine Receptor Calcium Release ChannelAnimalsDogsHumansMaleMiceMyocytes, CardiacCalciumryanodine receptor 1, mouseryanodine receptor 2. mouseRyanodine Receptor Calcium Release ChannelCa2+ releasecardiac hypertrophyheart failureRyR1RyR2
Identifiers
PMID42196272
PMCPMC13207715
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