Evidence map›Paper›PMID 42196222›Full record

ArticleInternational journal of molecular sciences2026

Comparative Metagenomic Studies Reveal Different Evolutionary Directions of Synthetic Indoor Microbial Communities Under Different Nutritional Conditions.

Xinyi Zhang, Lin Cai, Yukun Bai, Fang Peng

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xinyi ZhangChina Center for Type Culture Collection, College of Life Sciences, Wuhan University, Wuhan 430072, China.
Lin CaiChina Center for Type Culture Collection, College of Life Sciences, Wuhan University, Wuhan 430072, China.ORCID 0009-0003-4289-7995
Yukun BaiChina Center for Type Culture Collection, College of Life Sciences, Wuhan University, Wuhan 430072, China.ORCID 0000-0003-4433-2931
Fang PengChina Center for Type Culture Collection, College of Life Sciences, Wuhan University, Wuhan 430072, China.ORCID 0000-0002-6357-2378

Funding

Major Special Project on Agricultural Microbial Industry Development in Hubei Province NYWSWZX2025-2027-11Ministry of Science and Technology of the People's Republic of China 2022YFC2807501the R&D Infrastructure and Facility Development Program of the Ministry of Science and Technology of the People's Republic of China NIMR-2025-8
6 · The paper itself

Abstract

The relationship between microorganisms and human health is inseparable. In today's increasingly urbanized world, the relationship between indoor microbial communities and human health is particularly close. Studies have shown that the composition of indoor microbial communities is influenced by various factors, including temperature, humidity, and nutrient conditions. However, research on how to alter indoor microbial community structures by adjusting nutrient components to improve human health is still limited. In this work, we constructed artificial microbial communities composed of common indoor microorganisms, and analyzed the species composition, metabolic capabilities, antibiotic resistance, and virulence of the microbial communities before and after cultivation using metagenomic sequencing technologies and metatranscriptomic sequencing technologies. We then assessed their community characteristics and evolutionary direction under different nutrient conditions. Overall, when the nutrient conditions were altered and reduced, the evolutionary direction of indoor microbial communities changed significantly. Specifically, this evolutionary direction was manifested in a taxonomic succession of community composition, with marked shifts in the relative abundances of constituent species, as well as in a significant alteration of the community-level metabolic functions. In-depth research in this field can help improve the composition of indoor microbial communities, thereby benefiting human health and public health construction in urbanized environments.

Indexed as

BacteriaMetagenomeMetagenomicsMicrobiotaHumansNutrientshuman healthindoor microbial communitiesmetagenomicsmetatranscriptomicsmicrobial ecologysynthetic microbial communities

Identifiers

PMID42196222
PMCPMC13207052

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.