Evidence map›Paper›PMID 42196035›Full record

ReviewGels (Basel, Switzerland)2026

Preparation and Biomedical Applications of Spherical Cellulose Hydrogels: A Mini-Review.

Kaiqing Yang, Juping Zheng, Shiquan Shen, Chao Li, Yuzhu Song, Yichen Tian

Abstract readReview
In one paragraph

Review in Gels (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kaiqing YangResearch Center of Molecular Medicine of Yunnan Province, Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.ORCID 0000-0002-6866-5565
Juping ZhengResearch Center of Molecular Medicine of Yunnan Province, Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.ORCID 0009-0003-4010-789X
Shiquan ShenYunnan Provincial Key Laboratory of Tea Science, Tea Research Institute, Yunnan Academy of Agricultural Sciences, Kunming 650201, China.
Chao LiResearch Center of Molecular Medicine of Yunnan Province, Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
Yuzhu SongResearch Center of Molecular Medicine of Yunnan Province, Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
Yichen TianResearch Center of Molecular Medicine of Yunnan Province, Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.ORCID 0000-0003-1773-226X

Funding

Yunnan Province Science and Technology Department 202403AP140003Yunnan Province Science and Technology Department 202501CF070177
6 · The paper itself

Abstract

As the most abundant natural polymer on Earth, cellulose offers distinct advantages including renewability, biocompatibility, and modifiability. Among its various morphologies, spherical cellulose hydrogels (SCHs) represent a particularly versatile form ranging from micrometer to millimeter scales. They possess a unique hydrophilic 3D network, excellent flowability, high specific surface area, and outstanding mechanical stability, demonstrating great potential for biomedical applications. This mini-review highlights the primary bottom-up fabrication strategies for SCHs, including dripping, spraying, emulsion, and microfluidics, and the mechanisms by which different fabrication processes regulate their size, morphology, and structure are elucidated. On this basis, the recent advancements in SCHs across key biomedical domains, specifically in chromatographic separation, controlled drug delivery, tissue engineering, and wound healing, are discussed. Finally, the current challenges and future directions in this field are summarized and predicted, aiming to provide a reference for the development and application of high-performance cellulose-based biomaterials.

Indexed as

biomaterialsbiomedical applicationsbottom-up approachescontrolled drug deliveryfabrication processesspherical cellulose hydrogels

Identifiers

PMID42196035
PMCPMC13205944

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.