Evidence map›Paper›PMID 42196002›Full record

ArticleFoods (Basel, Switzerland)2026

Role of Germinated-Extruded Desi Chickpea Supplementation on Antioxidant and Antidiabetic Compounds In Vitro Bioaccessibility in Functional Blue Corn Tortillas.

Evelia M Milán-Noris, Victor M Hernández-Castro, Marilena Antunes-Ricardo, Alvaro Montoya-Rodríguez, Eslim S Sandoval-Sicairos, Jorge Milán-Carillo, Cuauhtémoc Reyes-Moreno, Ada K Milán-Noris

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Evelia M Milán-NorisLaboratorio de Nutracéuticos (#18), Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Sinaloa, Calz de las Américas Nte 2771, Cd Universitaria, Burócrata, Culiacán 80030, Sinaloa, Mexico.ORCID 0000-0002-4830-4789
Victor M Hernández-CastroLaboratorio de Nutracéuticos (#18), Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Sinaloa, Calz de las Américas Nte 2771, Cd Universitaria, Burócrata, Culiacán 80030, Sinaloa, Mexico.
Marilena Antunes-RicardoTecnologico de Monterrey, Escuela de Ingeniería y Ciencias, Av. Eugenio Garza Sada 2501 Sur, Tecnologico, Monterrey 64849, Nuevo Leon, Mexico.ORCID 0000-0002-8546-6832
Alvaro Montoya-RodríguezLaboratorio de Nutracéuticos (#18), Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Sinaloa, Calz de las Américas Nte 2771, Cd Universitaria, Burócrata, Culiacán 80030, Sinaloa, Mexico.ORCID 0000-0001-8358-0984
Eslim S Sandoval-SicairosLaboratorio de Nutracéuticos (#18), Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Sinaloa, Calz de las Américas Nte 2771, Cd Universitaria, Burócrata, Culiacán 80030, Sinaloa, Mexico.ORCID 0000-0002-9277-6118
Jorge Milán-CarilloLaboratorio de Nutracéuticos (#18), Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Sinaloa, Calz de las Américas Nte 2771, Cd Universitaria, Burócrata, Culiacán 80030, Sinaloa, Mexico.ORCID 0000-0002-7520-517X
Cuauhtémoc Reyes-MorenoLaboratorio de Nutracéuticos (#18), Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Sinaloa, Calz de las Américas Nte 2771, Cd Universitaria, Burócrata, Culiacán 80030, Sinaloa, Mexico.ORCID 0000-0002-4384-1286
Ada K Milán-NorisLaboratorio de Nutracéuticos (#18), Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Sinaloa, Calz de las Américas Nte 2771, Cd Universitaria, Burócrata, Culiacán 80030, Sinaloa, Mexico.

Funding

SECIHTI Ciencia de Frontera (263352)
6 · The paper itself

Abstract

Corn tortillas are consumed daily in Mexico. Alkaline extrusion is an alternative process that generates nixtamalized tortillas and preserves more bioactive compounds. Chickpea germination-extrusion may enhance the bioactive compound content. The aim was to characterize the physicochemical and antioxidant/antidiabetic properties of functional tortillas of alkaline-extruded blue corn (TC) with germinated (TG) or germinated-extruded (TGE) desi-chickpea. Likewise, the effect of simulated gastrointestinal digestion (SGD) on the bioaccessibility of bioactive compounds (phenolics, soluble protein, peptides, anthocyanins, and isoflavones) was estimated. Antioxidant capacity/cellular activity was determined by ORAC (AoxC) and in the Caco-2 cell line (CAA), while antidiabetic potential by α-amylase inhibition. The supplementation with processed chickpeas (TG/TGE) increased protein, ash, and isoflavone content (

Indexed as

antioxidantbioaccessibilitychickpeaextrusiongerminationtortilla

Identifiers

PMID42196002
PMCPMC13205625

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.