Evidence map›Paper›PMID 42195936›Full record

ArticleFoods (Basel, Switzerland)2026

In Vitro Fermentation of Green Tea by Human Gut Microbiota Enhances Bioactivity and Bidirectionally Modulates Polyphenol Metabolites and Gut Microbiota.

Kaiyin Hu, Jinxin Liu, You Su, Yijun Wang, Huimin Guo, Xiaochun Wan, Zhongwen Xie, Li Sun

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kaiyin HuThe College of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China.
Jinxin LiuThe College of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China.
You SuThe College of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China.
Yijun WangState Key Laboratory of Tea Plant Germplasm Innovation and Utilization, School of Tea Sciences, Anhui Agricultural University, Hefei 230036, China.
Huimin GuoCenter for Biotechnology, Anhui Agricultural University, Hefei 230036, China.
Xiaochun WanState Key Laboratory of Tea Plant Germplasm Innovation and Utilization, School of Tea Sciences, Anhui Agricultural University, Hefei 230036, China.
Zhongwen XieState Key Laboratory of Tea Plant Germplasm Innovation and Utilization, School of Tea Sciences, Anhui Agricultural University, Hefei 230036, China.ORCID 0000-0002-3080-4881
Li SunThe College of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China.

Funding

China Agriculture Research System CARS-19National Key Research and Development Program of China 2021YFD1601102
6 · The paper itself

Abstract

Green tea is highly popular due to its richness in polyphenols exhibiting broad bioactivities. Tea polyphenols, primarily catechins and flavonoids, demonstrate health benefits following biotransformation by the gut microbiota to overcome limited bioavailability. However, metabolites and interaction between green tea polyphenol and the gut microbiota remains to be fully elucidated. This study investigates the biotransformation of metabolites and interaction between human gut microbiota (HGM) and green tea extract (GTE) through in vitro anaerobic fermentation. Temporal bioactivity assessments demonstrated that fermentation-enhanced antioxidant capacity and inhibition potential of

Indexed as

bioactive metabolitesflavonoid metabolic pathwaygreen teagut microbial metabolismpolyphenol biotransformationuntargeted metabolomics

Identifiers

PMID42195936
PMCPMC13206288

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.