Evidence map›Paper›PMID 42195843›Full record

ArticleFoods (Basel, Switzerland)2026

Effect of Selenium-Enriched Donkey Milk on Lipid Metabolism Disorders Induced by a High-Fat Diet.

Qizhen Zhong, Jie Cheng, Gengli Huang, Julei Zhan, Xue Chen, Meixuan Liu, Guangyuan Liu, Zhuoru Ren, Xuemei Chen, Xiaoshu Tang and 1 more

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Qizhen ZhongState Key Laboratory of Food Science and Resources, Jiangnan University, Lihu Road 1800, Wuxi 214122, China.
Jie ChengShandong Key Laboratory of Gelatine Medicines Research and Development, Dong'e Ejiao Co., Ltd., Liaocheng 252200, China.
Gengli HuangState Key Laboratory of Food Science and Resources, Jiangnan University, Lihu Road 1800, Wuxi 214122, China.
Julei ZhanState Key Laboratory of Food Science and Resources, Jiangnan University, Lihu Road 1800, Wuxi 214122, China.
Xue ChenState Key Laboratory of Food Science and Resources, Jiangnan University, Lihu Road 1800, Wuxi 214122, China.
Meixuan LiuState Key Laboratory of Food Science and Resources, Jiangnan University, Lihu Road 1800, Wuxi 214122, China.
Guangyuan LiuShandong Key Laboratory of Gelatine Medicines Research and Development, Dong'e Ejiao Co., Ltd., Liaocheng 252200, China.
Zhuoru RenShandong Key Laboratory of Gelatine Medicines Research and Development, Dong'e Ejiao Co., Ltd., Liaocheng 252200, China.
Xuemei ChenNational Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, China.
Xiaoshu TangNational Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, China.
Zhouping WangState Key Laboratory of Food Science and Resources, Jiangnan University, Lihu Road 1800, Wuxi 214122, China.

Funding

National Natural Science Foundation of China 32372423 & 32302190Shandong Taishan Industrial Leading Talent Program tscx202408114
6 · The paper itself

Abstract

Selenium-enriched donkey milk (Se-DM) is characterized by low fat levels, low casein levels, high antioxidant activity, and high selenium content. To date, the regulatory role of Se-DM in the context of a high-fat diet (HFD) is unclear, prompting this present study to elucidate the potential mechanisms by which it affects the gut microbiota and hepatic lipid metabolism in rats fed a high-fat diet. The effects of Se-DM on fat accumulation and lipid peroxidation in HFD rats were investigated through non-targeted fecal metabolomics, short-chain fatty acid (SCFA) quantification, 16S microbial analysis, and pathological assessments. The results showed that Se-DM enhanced SCFA production by promoting Akkermansia muciniphila (

Indexed as

Akkermansia muciniphilaAMP-activated protein kinaseselenium-enriched donkey milkshort-chain fatty acid

Identifiers

PMID42195843
PMCPMC13206217

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.