ArticleMicromachines2026
Towards a Nitinol-Based Microfabricated Approach to Repair Long-Gap Esophageal Atresia.
Article in Micromachines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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12 authors.
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Abstract
Long-gap esophageal atresia is a congenital anomaly that requires challenging repair procedures that are often associated with complications. This work proposes the use of nitinol to repair long-gap esophageal atresia. A first proof-of-concept with commercial nitinol is presented. Experimental tests and simulations were performed, including the application of electrical currents to promote nitinol heating and consequent contraction, tensile tests, chemical analysis, and ex vivo tests using porcine esophageal tissues. A preliminary experiment is also presented regarding NiTi sputtering deposition and the morphological, chemical, and crystallographic analysis of the thin-films, featuring the implementation of a microfabricated solution. The experimental electrical tests were in accordance with the simulations. The nitinol electrical resistance (0.8-1.5 Ω) decreased as its temperature increased (20-60 °C) with the application of electrical current (<1 A), which was consistent with the experimental Seebeck coefficient (6.49 ± 0.46 µV/K). The measured forces (6.5 N at 45 °C) are also in accordance with traction sutures. Chemical analysis revealed a passive titanium dioxide layer reported for nitinol. Regarding the ex vivo tests, the average nitinol final length was 28.5 mm, below 30 mm (threshold for long-gap esophageal atresia). Finally, preliminary results from NiTi sputtering confirmed well-controlled deposition and the viability of scaling this approach, opening new avenues for nitinol-based biomedical devices.
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