ArticleMicromachines2026
Synthesis and Properties of SPI/PLA-PCL Composite Microspheres.
Article in Micromachines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Construction and Properties of SPI/PLA-PCL Composite Coating on Pure Titanium Surface.Micromachines · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
According to the complementary advantages of the composites, the degradation rate, biological activity and physical and chemical properties of the composites were adjusted by using the hydrophilic and bioactive advantages of soy protein isolate (SPI) on the basis of toughening PLA by polycaprolactone (PCL). In this study, soy protein isolate/polylactic acid-polycaprolactone (SPI/PLA-PCL) composite microspheres were fabricated via double emulsion-solvent evaporation. SPI was introduced to regulate hydrophilicity, biodegradation, and bioactivity based on PCL-toughened PLA. The microspheres were characterized by SEM, EDS, FTIR, and XRD. Hydrophilicity, thermal stability, and degradation behavior were evaluated via water contact angle, TG/DTA, and in vitro degradation assays. Biocompatibility, hemocompatibility, and osteogenic activity were assessed through cell adhesion, hemolysis, CCK-8, ALP, alizarin red staining, and mineralization tests. Results confirmed the successful preparation of SPI/PLA-PCL microspheres. SPI incorporation enhanced hydrophilicity, degradation rate, and cell adhesion. The composite microspheres exhibited favorable thermal stability, hemocompatibility, biocompatibility, and osteogenic induction. The 50% SPI/PLA-PCL group performed optimally in cell proliferation, adhesion, ALP activity, and mineralization, demonstrating promising potential for bone tissue engineering applications.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.