ArticleMicromachines2026
A Droplet-Based Microfluidic Platform for Rapid Optical Detection of Bacteria: Proof-of-Concept for Radiopharmaceutical Sterility Testing.
Article in Micromachines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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8 authors.
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Abstract
Rapid sterility testing of radiopharmaceuticals is essential due to their short half-lives and strict safety requirements. Conventional culture-based methods require several days and are not compatible with clinical workflows. In this work, we present a proof-of-concept droplet-based microfluidic platform for rapid optical detection of bacterial contamination through optical extinction analysis of microdroplets. Monodisperse water-in-oil microdroplets were generated and optically interrogated using a fiber-based detection system. Calibration was first performed using 500 nm polystyrene nanoparticles to establish the relationship between particle concentration and optical extinction. Subsequently,
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