Pressure Modulation of Fluidic Patterns Inside the Nanochannel for Two States of Ionic Conductance.

Xiaojie Li, Xingye Zhang, Yang Liu, Zhen Cao, Xin Zhu, Zhi Ye

Abstract read

In one paragraph

Article in Micromachines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Xiaojie LiCollege of Information Science and Electronic Engineering, Zhejiang University, Hangzhou 310058, China.

Xingye ZhangCollege of Information Science and Electronic Engineering, Zhejiang University, Hangzhou 310058, China.

Yang LiuCollege of Information Science and Electronic Engineering, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0002-7411-8779

Zhen CaoCollege of Information Science and Electronic Engineering, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0002-5440-3628

Xin ZhuCollege of Information Science and Electronic Engineering, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0002-9413-7125

Zhi YeCollege of Information Science and Electronic Engineering, Zhejiang University, Hangzhou 310058, China.

Funding

China Postdoctoral Science Foundation 2015M581931Key Research and Development Program of Zhejiang Province 2025C02154National Natural Science Foundation of China 61574126, 61774132, 61701438Natural Science Foundation of Zhejiang Province LD25F040003Natural Science Foundation of Zhejiang Province, China LR15F040001

6 · The paper itself

Abstract

This work numerically reveals a novel strategy to modulate two ionic conductance state in a nanochannel via pressure-dependent fluidic motion inside the channel. Steady and transient simulations based on Poisson-Nernst-Planck-Stokes equations demonstrate that the two states with distinct ionic conductance and ion selectivity can be reversibly switched by external pressure, with a characteristic time of ~100 μs. Furthermore, the two conductance states are found to depend on the transversal electric field, which gives rise to two distinct intrachannel fluidic flow patterns, namely laminar flow and vortex flow, respectively. This finding suggests the potential of pressure-controlled ionic conductance switching for applications in nanofluidic ionic circuits, flow-regulated sensing, and integrated micro/nanoscale devices. It also provides insights into nonlinear ionic current-voltage behaviors.

Indexed as

nanochannelnanofluidicsPoisson–Nernst–Planck–Stokes simulation

Identifiers

PMID42195424

DOI10.3390/mi17050506

PMCPMC13209024

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LicenceCC BY

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.