ArticleLife (Basel, Switzerland)2026
Dynamic Changes in Optic Nerve Sheath Diameter on Computed Tomography Predict Decompressive Efficacy and Outcomes in Severe Traumatic Brain Injury.
Article in Life (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Elevated intracranial pressure (ICP) is a major determinant of secondary injury and mortality in severe traumatic brain injury (TBI), yet objective markers of decompressive craniectomy (DC) efficacy remain limited. Optic nerve sheath diameter (ONSD), measurable on computed tomography (CT), has emerged as a non-invasive surrogate of ICP. This study evaluated the relationship between perioperative ONSD changes and clinical and surgical parameters in patients undergoing DC. In this retrospective cohort study, 72 patients with severe TBI were included. ONSD was measured on preoperative and early postoperative CT, and the change (ΔONSD) was analyzed in relation to craniectomy surface area and outcomes. DC resulted in a significant reduction in ONSD (6.44 ± 0.88 mm vs. 5.55 ± 0.82 mm,
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