Evidence map›Paper›PMID 42195342›Full record

ArticleLife (Basel, Switzerland)2026

Aglianico Grape Pomace Extract Reduces Cardiac Pacemaker Activity by Decreasing Hyperpolarization-Activated Current Density Independently of cAMP Signaling.

Roberta De Zio, Maira Certini, Eugenia Pignataro, Daniela Russo, Simona Ida Scorza, Serena Milano, Giuseppe Procino, René Massimiliano Marsano, Maria Svelto, Isabella Maiellaro and 3 more

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Roberta De ZioDepartment of Biosciences, Biotechnology and Environment, University of Bari Aldo Moro, 70125 Bari, Italy.ORCID 0000-0002-1777-2088
Maira CertiniDepartment of Biosciences, Biotechnology and Environment, University of Bari Aldo Moro, 70125 Bari, Italy.
Eugenia PignataroDepartment of Biosciences, Biotechnology and Environment, University of Bari Aldo Moro, 70125 Bari, Italy.ORCID 0009-0002-1822-5892
Daniela RussoDepartment of Health Sciences, University of Basilicata, 85100 Potenza, Italy.ORCID 0000-0002-3086-784X
Simona Ida ScorzaDepartment of Biosciences, Biotechnology and Environment, University of Bari Aldo Moro, 70125 Bari, Italy.
Serena MilanoDepartment of Health Sciences, University of Basilicata, 85100 Potenza, Italy.
Giuseppe ProcinoDepartment of Biosciences, Biotechnology and Environment, University of Bari Aldo Moro, 70125 Bari, Italy.ORCID 0000-0002-0043-7523
René Massimiliano MarsanoDepartment of Biosciences, Biotechnology and Environment, University of Bari Aldo Moro, 70125 Bari, Italy.ORCID 0000-0001-8450-1010
Maria SveltoDepartment of Biosciences, Biotechnology and Environment, University of Bari Aldo Moro, 70125 Bari, Italy.
Isabella MaiellaroSchool of Life Sciences, Department of Neuroscience, University of Nottingham, Nottingham NG7 2RD, UK.ORCID 0000-0001-5595-8011
Luigi MilellaDepartment of Health Sciences, University of Basilicata, 85100 Potenza, Italy.ORCID 0000-0002-5874-1237
Monica CarmosinoDepartment of Health Sciences, University of Basilicata, 85100 Potenza, Italy.
Andrea GerbinoDepartment of Biosciences, Biotechnology and Environment, University of Bari Aldo Moro, 70125 Bari, Italy.ORCID 0000-0002-2839-0130

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Grape pomace extract (GPE) from

Indexed as

cAMPcardiac pacemakerchronotropydiastolic depolarizationDrosophila melanogasterfunny currentgrape pomace extractHCN channelsHL-1 cardiomyocytespolyphenols

Identifiers

PMID42195342
PMCPMC13208127

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.