ArticleLife (Basel, Switzerland)2026
From Serum to Genome: γ-Glutamyltransferase Gene Family Variants Shape Ischemic Stroke Risk via Sex-Specific Gene-Environment Interactions.
Maria Solodilova, Elena Drozdova, Iuliia Azarova, Marina Bykanova, Olga Bushueva, Anna Puchkova, Vyacheslav Puchkov, Maxim Freidin, Mikhail Churnosov, Alexey Polonikov
Abstract read
In one paragraphArticle in Life (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
10 authors.
Maria SolodilovaDepartment of Biology, Medical Genetics and Ecology, Kursk State Medical University, 3 Karl Marx Street, Kursk 305041, Russia.
Elena DrozdovaDepartment of General Hygiene, Kursk State Medical University, 3 Karl Marx Street, Kursk 305041, Russia.
Iuliia AzarovaDepartment of Biological and Chemical Technology, Kursk State Medical University, 18 Yamskaya St., Kursk 305041, Russia.ORCID 0000-0001-8098-8052 Marina BykanovaLaboratory of Genomic Research, Research Institute for Genetic and Molecular Epidemiology, Kursk State Medical University, 18 Yamskaya St., Kursk 305041, Russia.
Olga BushuevaDepartment of Biology, Medical Genetics and Ecology, Kursk State Medical University, 3 Karl Marx Street, Kursk 305041, Russia.ORCID 0000-0003-3333-0623 Anna PuchkovaDepartment of Biology, Medical Genetics and Ecology, Kursk State Medical University, 3 Karl Marx Street, Kursk 305041, Russia.
Vyacheslav PuchkovDepartment of Biology, Medical Genetics and Ecology, Kursk State Medical University, 3 Karl Marx Street, Kursk 305041, Russia.
Maxim FreidinDepartment of Twin Research and Genetic Epidemiology, King's College London, Westminster Bridge Rd, London SE1 7EH, UK.
Mikhail ChurnosovDepartment of Medical Biological Disciplines, Belgorod State University, 85 Pobedy Street, Belgorod 308015, Russia.ORCID 0000-0003-1254-6134 Alexey PolonikovDepartment of Biology, Medical Genetics and Ecology, Kursk State Medical University, 3 Karl Marx Street, Kursk 305041, Russia.ORCID 0000-0001-6280-247X Funding
Russian Science Foundation 25-25-00840
6 · The paper itselfAbstract
Serum gamma-glutamyltransferase (GGT) is a biomarker for cardiovascular disease, but the role of its encoding gene family in ischemic stroke (IS) is unknown. This pilot study of 1288 individuals (600 cases and 688 controls) investigated
Indexed as
gamma-glutamyl transferasegene–environment interactionsgene–gene interactionsischemic strokelifestyle factorssingle nucleotide polymorphism
Identifiers
PMID42195278
PMCPMC13208725
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