Evidence map›Paper›PMID 42195059›Full record

ArticleMedicina (Kaunas, Lithuania)2026

Integrated Chemometric and Machine Learning Analysis Identifies Peripheral Biosignatures Distinguishing Major Depressive Disorder from Bipolar Disorder: A Translational Cross-Sectional Study.

Donatella Coradduzza, Stefania Sedda, Andrea Sanna, Alessandra Matilde Nivoli, Maria Rosaria De Miglio, Ciriaco Carru, Massimiliano Grosso, Serenella Medici

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Donatella CoradduzzaDepartment of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-8978-0490
Stefania SeddaDepartment of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.
Andrea SannaSC Chimica Istituto Zooprofilattico Sperimentale della Sardegna, Via Duca degli Abruzzi, 8, 07100 Sassari, Italy.ORCID 0000-0003-3024-4527
Alessandra Matilde NivoliDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-0494-2084
Maria Rosaria De MiglioDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-9393-3234
Ciriaco CarruDepartment of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-6985-4907
Massimiliano GrossoDepartment of Mechanical, Chemical and Materials Engineering, University of Cagliari, 09124 Cagliari, Italy.ORCID 0000-0002-7793-3920
Serenella MediciDepartment of Chemical, Physical, Mathematical and Natural Sciences, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-4304-0251

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bipolar DisorderMachine LearningMajor Depressive DisorderAdultBiomarkersCross-Sectional StudiesDiagnosis, DifferentialFemaleHumansMaleMiddle AgedNLR Family, Pyrin Domain-Containing 3 ProteinBiomarkersNLR Family, Pyrin Domain-Containing 3 Proteinbipolar disorderchemometricsmachine learningmajor depressive disordermetallomicsNLRP3 inflammasomepartial least squares discriminant analysisperipheral inflammationprincipal component analysistranslational biomarkers

Identifiers

PMID42195059
PMCPMC13208896

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.