Evidence map›Paper›PMID 42194656›Full record

ArticleJournal of clinical medicine2026

Consensus Statement on Full-Arch Implant Rehabilitations: Evidence-Based Recommendations from the Italian Consensus Conference.

Biagio Rapone, Elisabetta Ferrara, Filippo Tomarelli, Giuseppe Giovannico, Christian Bacci, Grazieli Dalmaschio, Massimiliano Novello, Antonio Andrisani, Giuseppe De Caro, Elena Fontanella and 19 more

Abstract readComment
In one paragraph

Article in Journal of clinical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Biagio RaponeInterdisciplinary Department of Medicine, "Aldo Moro" University of Bari, 70121 Bari, Italy.ORCID 0000-0002-0062-6594
Elisabetta FerraraDepartment of Human Sciences, Law, and Economics, Telematic University "Leonardo Da Vinci", UNIDAV, Torrevecchia Teatina, 66100 Chieti, Italy.ORCID 0000-0002-4831-4098
Filippo TomarelliPrivate Practice, 00197 Rome, Italy.
Giuseppe GiovannicoDepartment of Medicine and Health Science "Vincenzo Tiberio", University of Molise, 86100 Campobasso, Italy.ORCID 0000-0003-2385-6816
Christian BacciDepartment of Neurosciences, University of Padua, 35122 Padua, Italy.ORCID 0000-0002-6956-6227
Grazieli DalmaschioDepartment of Neurosciences, University of Padua, 35122 Padua, Italy.
Massimiliano NovelloPrivate Practice, 00197 Rome, Italy.
Antonio AndrisaniPrivate Practice, 00197 Rome, Italy.
Giuseppe De CaroSelf-Employed Owner of a Dental Laboratory, 31044 Montebelluna (TV), Italy.
Elena FontanellaPrivate Practice, 00197 Rome, Italy.
Paolo Dal MasoSelf-Employed Owner of a Dental Laboratory, 31044 Montebelluna (TV), Italy.
Alessandro BusoPrivate Practice, 00197 Rome, Italy.
Alberto RagagninPrivate Practice, 00197 Rome, Italy.
Marco RondaPrivate Practice, 00197 Rome, Italy.
Fabio BernardelloPrivate Practice, 00197 Rome, Italy.ORCID 0000-0001-6432-1549
Carlo BaronciniSelf-Employed Owner of a Dental Laboratory, 31044 Montebelluna (TV), Italy.
Salvatore GalentinoPrivate Practice, 00197 Rome, Italy.
Danilo AzzoliniSelf-Employed Owner of a Dental Laboratory, 31044 Montebelluna (TV), Italy.
Nicola BarionPrivate Practice, 00197 Rome, Italy.
Paolo BozzoliPrivate Practice, 00197 Rome, Italy.
Vittorio GiannelliPrivate Practice, 00197 Rome, Italy.
Alessandro MazzottaPrivate Practice, 00197 Rome, Italy.
Filippo MuratorePrivate Practice, 00197 Rome, Italy.
Maurizio GrandePrivate Practice, 00197 Rome, Italy.
Costantino Giagnorio"Policlinico Foggia" University Hospital, 71122 Foggia, Italy.
Caterina NardiPrivate Practice, 00197 Rome, Italy.
Gilberto GallelliSelf-Employed Owner of a Dental Laboratory, 31044 Montebelluna (TV), Italy.
Luca ErbosoPrivate Practice, 00197 Rome, Italy.
Maurizio De FrancescoDepartment of Neurosciences, University of Padua, 35122 Padua, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Full-arch implant-supported rehabilitations are widely recognized as an effective treatment option for edentulous patients. Nevertheless, clinical decision-making regarding patient selection, surgical planning, prosthetic material choice, and long-term maintenance protocols remains heterogeneous and requires structured evidence-based guidance. A modified Delphi consensus process was conducted involving 29 experts during the Italian Consensus Conference. A systematic literature review covering the period 2015-2024 was performed, and the certainty of evidence was assessed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) framework. Consensus was predefined as ≥90% agreement. Seven evidence-based consensus statements were developed addressing: (1) periodontal risk assessment using validated tools; (2) guided bone regeneration outcomes with technique-specific indications; (3) comparative survival of four versus six implants in mandibular full-arch rehabilitations; (4) equivalence of tilted and axial implant configurations; (5) prosthetic material selection, with monolithic zirconia showing high survival; (6) risk-stratified supportive maintenance protocols associated with a reduction in peri-implantitis incidence; and (7) systemic risk stratification, including absolute and relative contraindications, medication-related osteonecrosis of the jaw (MRONJ) risk management, and perioperative antibiotic prophylaxis.

Indexed as

All-on-4consensus statementDelphi methoddental implantsfull-arch rehabilitationGRADEguided bone regenerationmaintenance protocolmonolithic zirconiaMRONJperi-implantitis

Identifiers

PMID42194656
PMCPMC13207077

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.