Evidence map›Paper›PMID 42194314›Full record

ReviewBioengineering (Basel, Switzerland)2026

Bridging the Gap in Cryopreservation: A Review of Cryoprotectant Innovation and Global Market Trends.

Shankar Shanmuga Sundaram, Quang Bach Le, Deepak Choudhury

Abstract readReview
In one paragraph

Review in Bioengineering (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shankar Shanmuga SundaramBioengineering and Automation (BE&A), Bioprocessing Technology Institute (BTI), Agency for Science, Technology, and Research (A*STAR), Singapore 138669, Singapore.ORCID 0009-0000-4134-5433
Quang Bach LeBioengineering and Automation (BE&A), Bioprocessing Technology Institute (BTI), Agency for Science, Technology, and Research (A*STAR), Singapore 138669, Singapore.ORCID 0000-0002-1001-4751
Deepak ChoudhuryBioengineering and Automation (BE&A), Bioprocessing Technology Institute (BTI), Agency for Science, Technology, and Research (A*STAR), Singapore 138669, Singapore.ORCID 0000-0001-9609-1346

Funding

National Medical Research Council MOH-OFIRG24jul-0017
6 · The paper itself

Abstract

Cryopreservation integrates technologies that enable the long-term preservation of biological materials at extremely low temperatures. Since the serendipitous discovery by Audrey Smith and Christopher Polge that glycerol enhances the survival of frozen chicken sperm, the field has advanced rapidly and found applications across cell therapy, biobanking, and tissue engineering. This concise review provides an overview of cryopreservation principles and the current commercial landscape in cell freezing media, highlighting key players, challenges and recent developments in tissue and small-organ preservation.

Indexed as

cell therapyCPAscryopreservationcryoprotective agentstissue engineeringtissue regenerationtissue therapy

Identifiers

PMID42194314
PMCPMC13203093

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.