Evidence map›Paper›PMID 42194118›Full record

ArticleChildren (Basel, Switzerland)2026

Ketosis Home Management in Pediatric Type 1 Diabetes in Germany: Mismatch Between Subjective Self-Ratings and Objectively Assessed Competence in Preventing Diabetic Ketoacidosis.

Simone Eisenhofer, Martina Patrizia Neininger, Astrid Bertsche, Wieland Kiess, Thilo Bertsche, Thomas Michael Kapellen

Abstract read
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Article in Children (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Simone EisenhoferDrug Safety Center, Leipzig University Hospital, Leipzig University, Brüderstrasse 32, 04103 Leipzig, Germany.
Martina Patrizia NeiningerDrug Safety Center, Leipzig University Hospital, Leipzig University, Brüderstrasse 32, 04103 Leipzig, Germany.ORCID 0000-0002-5208-0888
Astrid BertscheDepartment of Neuropediatrics and Metabolic Diseases, University Medicine Greifswald, Ferdinand-Sauerbruch-Strasse 1, 17475 Greifswald, Germany.ORCID 0000-0003-2832-0156
Wieland KiessCenter for Pediatric Research, University Hospital for Children and Adolescents, Liebigstrasse 20a, 04103 Leipzig, Germany.
Thilo BertscheDrug Safety Center, Leipzig University Hospital, Leipzig University, Brüderstrasse 32, 04103 Leipzig, Germany.ORCID 0000-0002-4930-6655
Thomas Michael KapellenCenter for Pediatric Research, University Hospital for Children and Adolescents, Liebigstrasse 20a, 04103 Leipzig, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEffective sick-day management, including ketosis home management aimed at preventing diabetic ketoacidosis (DKA), is essential for families living with a child/adolescent with type 1 diabetes (T1D).

methodsAdolescents living with T1D and caregivers of younger children living with T1D were invited to participate in an interview consisting of five parts: (I) demographic data, (II) subjective self-ratings on competence in ketosis home management, (III) objective assessment of competence in ketosis home management using a standardized clinical case scenario consisting of 10 management steps, in which participants were asked to describe the actions they would take to prevent DKA, and (IV) practical demonstrations to objectively assess skills in (IVa) urine dipstick self-testing and (IVb) insulin administration, (V) household availability of (Va) urine dipsticks and (Vb) insulin cartridges.

results(I) We enrolled 61 adolescents and 79 caregivers. (II) Competence in ketosis home management was subjectively self-rated as good to very good. (III) Adolescents reported 4 (median; Q25/Q75 3/5) and caregivers 5 (4/5) of 10 management steps. Never self-testing ketone levels was reported by 33% of adolescents and 11% of caregivers. (IVa) At least one handling error occurred in 100% of adolescents' and in 98% of caregivers' practical demonstrations of urine dipstick self-testing and in (IVb) 98% of adolescents' and 98% of caregivers' insulin administrations. (Va) Altogether urine dipsticks were available in 43% of households, whereas (Vb) insulin cartridges were available in 78% of households.

conclusionsOur results demonstrate a mismatch between challenges in ketosis home management and high subjective self-ratings.

Indexed as

diabetes mellitusdiabetic ketoacidosis (DKA)diabetic ketosisinsulin administrationketone testingsick-day managementtype 1 diabetes (T1D)urine dipsticks

Identifiers

PMID42194118
PMCPMC13204090

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