Evidence map›Paper›PMID 42194117›Full record

ArticleChildren (Basel, Switzerland)2026

Single-Stage Combined Embolization and Structural Allograft Reconstruction for Proximal Humerus Aneurysmal Bone Cysts in Children.

Maximilian Leiblein, Johannes Frank, Ingo Marzi, Katharina Sommer, Katrin Eichler, Thomas Vogl, Nils Wagner

Abstract read
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Article in Children (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Maximilian LeibleinDepartment of Trauma Surgery and Orthopedics, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.
Johannes FrankDepartment of Trauma Surgery and Orthopedics, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.
Ingo MarziDepartment of Trauma Surgery and Orthopedics, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.
Katharina SommerDepartment of Trauma Surgery and Orthopedics, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.
Katrin EichlerInstitute for Diagnostic and Interventional Radiology, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.
Thomas VoglInstitute for Diagnostic and Interventional Radiology, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.
Nils WagnerDepartment of Trauma Surgery and Orthopedics, University Hospital, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAneurysmal bone cysts (ABCs) of the proximal humerus in children are rare, locally aggressive lesions associated with substantial recurrence rates and risk of structural instability. Conventional treatment by curettage and bone grafting is often limited by recurrence, while selective arterial embolization (SAE) alone may not provide sufficient structural support. This study evaluates a single-stage treatment strategy combining embolization and structural reconstruction to address both the vascular and mechanical components of the disease.

methodsA retrospective analysis was performed on 12 pediatric patients (median age 9 years) with proximal humerus ABCs treated between 2020 and 2024. All patients underwent a standardized single-stage protocol consisting of preoperative SAE, intralesional resection with high-speed burr, and reconstruction using an allogeneic fibula graft combined with cancellous bone augmentation. Radiological consolidation, recurrence, and functional outcomes were assessed. Associations between prior surgery, cyst size, and recurrence were analyzed.

resultsPrimary consolidation was achieved in 75% of patients, with an overall healing rate of 91.7% after secondary interventions. Recurrence occurred in 16.7% of cases and was significantly associated with prior surgical treatment (

conclusionsThe presented single-stage approach combining SAE, intralesional resection, and structural allograft reconstruction addresses both the vascular supply and mechanical instability of proximal humerus ABCs. This strategy demonstrated high healing rates and favorable functional outcomes, with acceptable recurrence rates in this cohort while avoiding donor site morbidity. It represents a practical and effective treatment concept for this rare pediatric condition.

Indexed as

allograft reconstructionaneurysmal bone cystbone tumorfibular graftpediatricproximal humerusselective arterial embolization

Identifiers

PMID42194117
PMCPMC13204050

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