ArticleBiomolecules2026
Optimized LL-37-Derived Peptides Exhibit Antitubercular Activity, Induce Membrane Disruption, and P-Type ATPase Transcriptional Responses in
Paola A Santos, Milena Maya-Hoyos, Luz Mary Salazar, Claudia Andrea Cruz, Alver Cruz-Cacais, Mayerly Giraldo-Avila, Juliana Gómez-Manchego, Lineth Valentina Triana, Carlos Y Soto
Abstract read
In one paragraphArticle in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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5 · Who and what moneyAuthors and funding
9 authors.
Paola A SantosBioquímica y Biología Molecular de las Micobacterias-BBMM, Departamento de Química, Facultad de Ciencias, Universidad Nacional de Colombia, Carrera 30 N° 45-03, Bogotá 111321, Colombia.ORCID 0000-0002-7356-083X Milena Maya-HoyosBioquímica y Biología Molecular de las Micobacterias-BBMM, Departamento de Química, Facultad de Ciencias, Universidad Nacional de Colombia, Carrera 30 N° 45-03, Bogotá 111321, Colombia.ORCID 0000-0001-7752-4636 Luz Mary SalazarBioquímica y Biología Molecular de las Micobacterias-BBMM, Departamento de Química, Facultad de Ciencias, Universidad Nacional de Colombia, Carrera 30 N° 45-03, Bogotá 111321, Colombia.
Claudia Andrea CruzRelaciones Microbianas y Epidemiológicas Aplicadas al Laboratorio Clínico y Molecular-REMA, Facultad de Ciencias de la Salud, Universidad Colegio Mayor de Cundinamarca, Calle 28 N° 5B-02, Bogotá 110311, Colombia.
Alver Cruz-CacaisBioquímica y Biología Molecular de las Micobacterias-BBMM, Departamento de Química, Facultad de Ciencias, Universidad Nacional de Colombia, Carrera 30 N° 45-03, Bogotá 111321, Colombia.ORCID 0000-0001-8208-863X Mayerly Giraldo-AvilaBioquímica y Biología Molecular de las Micobacterias-BBMM, Departamento de Química, Facultad de Ciencias, Universidad Nacional de Colombia, Carrera 30 N° 45-03, Bogotá 111321, Colombia.ORCID 0009-0004-9694-3958 Juliana Gómez-ManchegoBioquímica y Biología Molecular de las Micobacterias-BBMM, Departamento de Química, Facultad de Ciencias, Universidad Nacional de Colombia, Carrera 30 N° 45-03, Bogotá 111321, Colombia.
Lineth Valentina TrianaRelaciones Microbianas y Epidemiológicas Aplicadas al Laboratorio Clínico y Molecular-REMA, Facultad de Ciencias de la Salud, Universidad Colegio Mayor de Cundinamarca, Calle 28 N° 5B-02, Bogotá 110311, Colombia.
Carlos Y SotoBioquímica y Biología Molecular de las Micobacterias-BBMM, Departamento de Química, Facultad de Ciencias, Universidad Nacional de Colombia, Carrera 30 N° 45-03, Bogotá 111321, Colombia.ORCID 0000-0001-8694-7489 Funding
Sistema Universitario Estatal - SUE grant number 60896
6 · The paper itselfAbstract
Tuberculosis (TB), caused by
Indexed as
Adenosine TriphosphatasesAntimicrobial Cationic PeptidesAntitubercular AgentsCathelicidinsCell MembraneMycobacterium tuberculosisTranscription, GeneticAmino Acid SequenceHumansMicrobial Sensitivity TestsAdenosine TriphosphatasesAntimicrobial Cationic PeptidesAntitubercular AgentsCathelicidinsantimicrobial peptidesLL37 analog peptidesMycobacterium tuberculosisP-type ATPases
Identifiers
PMID42194015
PMCPMC13204550
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