Evidence map›Paper›PMID 42193994›Full record

ArticleBiomolecules2026

Association of the Dedicator of Cytokinesis 2 (DOCK2) Gene Polymorphisms with COVID-19 and Plasma LDH, AST, ALT, and Ferritin Levels.

José Manuel Fragoso, Rosalinda Posadas-Sánchez, Alberto López-Reyes, Laura E Martínez-Gómez, Julian Ramírez-Bello, Giovanny Fuentevilla-Alvarez, Gilberto Vargas-Alarcón

Abstract read
In one paragraph

Article in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

José Manuel FragosoDepartament of Molecular Biology, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City 14080, Mexico.ORCID 0000-0003-3137-7815
Rosalinda Posadas-SánchezDepartment of Endocrinology, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City 14080, Mexico.ORCID 0000-0001-8467-3488
Alberto López-ReyesGeroscience Laboratory, Instituto Nacional de Rehabilitación "Luis Guillermo Ibarra Ibarra", Mexico City 14389, Mexico.ORCID 0000-0002-2575-2589
Laura E Martínez-GómezGeroscience Laboratory, Instituto Nacional de Rehabilitación "Luis Guillermo Ibarra Ibarra", Mexico City 14389, Mexico.
Julian Ramírez-BelloClinical Research, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City 14080, Mexico.ORCID 0000-0002-4153-9315
Giovanny Fuentevilla-AlvarezDepartment of Endocrinology, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City 14080, Mexico.ORCID 0000-0002-1819-8444
Gilberto Vargas-AlarcónResearch Direction and Molecular Biology Department, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano No. 1, Tlalpan, Mexico City 14080, Mexico.ORCID 0000-0001-7916-5163

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case-control study investigated the association between polymorphisms in the dedicator of cytokinesis 2 (

methodsGenotyping of five single-nucleotide polymorphisms (SNPs) in the

resultsNo significant differences were observed in the allelic or genotypic distributions of rs1045176

conclusionsThe

Indexed as

Alanine TransaminaseAspartate AminotransferasesCOVID-19FerritinsGTPase-Activating ProteinsGuanine Nucleotide Exchange FactorsL-Lactate DehydrogenasePolymorphism, Single NucleotideAdultCase-Control StudiesFemaleGenetic Predisposition to DiseaseGenotypeHumansMaleMexicoAlanine TransaminaseAspartate AminotransferasesDOCK2 protein, humanFerritinsGTPase-Activating ProteinsGuanine Nucleotide Exchange FactorsL-Lactate DehydrogenaseCOVID-19dedicator of cytokinesis 2 (DOCK2)geneticsSARS-CoV-2susceptibility

Identifiers

PMID42193994
PMCPMC13204226

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.