Evidence map›Paper›PMID 42193991›Full record

ArticleBiomolecules2026

PEG-Dependent Tunable Degradation and Curcumin Release from Curcumin-Based Biomedical Polyurethanes.

Man Wang, Hongying Liu, Wei Zhao, Huafen Wang, Yuwei Zhuang, Ran Zhang, Zhaohui Liu, Nengwen Ke, Sichong Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Man WangHigh & New Technology Research Center of Henan Academy of Sciences, No. 56 Hongzhuan Road, Zhengzhou 450002, China.ORCID 0009-0002-3907-3656
Hongying LiuWest China School of Nursing, Sichuan University, No. 37, Guoxue Alley, Chengdu 610041, China.
Wei ZhaoHigh & New Technology Research Center of Henan Academy of Sciences, No. 56 Hongzhuan Road, Zhengzhou 450002, China.
Huafen WangHigh & New Technology Research Center of Henan Academy of Sciences, No. 56 Hongzhuan Road, Zhengzhou 450002, China.
Yuwei ZhuangHigh & New Technology Research Center of Henan Academy of Sciences, No. 56 Hongzhuan Road, Zhengzhou 450002, China.
Ran ZhangHigh & New Technology Research Center of Henan Academy of Sciences, No. 56 Hongzhuan Road, Zhengzhou 450002, China.
Zhaohui LiuHigh & New Technology Research Center of Henan Academy of Sciences, No. 56 Hongzhuan Road, Zhengzhou 450002, China.
Nengwen KeWest China School of Nursing, Sichuan University, No. 37, Guoxue Alley, Chengdu 610041, China.ORCID 0000-0002-7135-2244
Sichong ChenThe Collaborative Innovation Center for Eco-Friendly and Fire-Safety Polymeric Materials (MoE), National Engineering Laboratory of Eco-Friendly Polymeric Materials (Sichuan), College of Chemistry, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610064, China.

Funding

Henan Academy of Sciences 20250104Henan Academy of Sciences 20260602001; 20260602003Henan Academy of Sciences 20262302001Henan Academy of Sciences 241802039Henan Science and Technology Department 252102231011
6 · The paper itself

Abstract

Curcumin, a plant-derived polyphenolic compound, exhibits diverse pharmacological activities such as antioxidant, anti-inflammatory, anticancer, neuroprotective, and cardiovascular protective effects, and is widely used in food, medicine, and other fields. However, its poor water solubility and easy oxidative degradation limit its extensive application in biomedicine. To solve these problems, a series of biomedical polyurethanes (Cur-PU) with similar molecular weights but different PEG contents were successfully synthesized using HO-PCL-OH and HO-PEG-OH as soft segments and curcumin as a chain extender. The results indicated that increasing the PEG content reduced the T

Indexed as

CurcuminPolyethylene GlycolsPolyurethanesAnti-Bacterial AgentsAntioxidantsBiocompatible MaterialsDrug LiberationSolubilityAnti-Bacterial AgentsAntioxidantsBiocompatible MaterialsCurcuminPolyethylene GlycolsPolyurethanesbiocompatibilitybiodegradabilitycurcumin deliveryPEG-dependentpolyurethane

Identifiers

PMID42193991
PMCPMC13204639

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.