Evidence map›Paper›PMID 42193874›Full record

ArticleCells2026

TRPA1 and TRPV1 Receptors Protect the Gastric Mucosa from Ethanol-Induced Injury: Evidence from Knockout Mice.

Michal Zalecki, József Kun, Judyta Juranek, Hanna Antushevich, Zsuzsanna Helyes, Erika Pintér

Abstract read
In one paragraph

Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michal ZaleckiDepartment of Animal Anatomy, Faculty of Veterinary Medicine, University of Warmia and Mazury, Oczapowskiego 13 Street, 10-719 Olsztyn, Poland.ORCID 0000-0003-1626-218X
József KunDepartment of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, 12 Szigeti Street, 7624 Pécs, Hungary.ORCID 0000-0001-9607-305X
Judyta JuranekDepartment of Human Physiology and Pathophysiology, School of Medicine, Collegium Medicum, University of Warmia and Mazury, Warszawska 30 Street, 10-082 Olsztyn, Poland.
Hanna AntushevichDepartment of Genetic Engineering, The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Instytucka 3 Street, 05-110 Jabłonna, Poland.
Zsuzsanna HelyesDepartment of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, 12 Szigeti Street, 7624 Pécs, Hungary.
Erika PintérDepartment of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, 12 Szigeti Street, 7624 Pécs, Hungary.ORCID 0000-0001-9898-632X

Funding

Ministry of Science and Higher Education Funded by the Minister of Science under the Regional Initiative of Excellence Program
6 · The paper itself

Abstract

Ethanol disrupts gastric mucosal integrity and induces inflammation. Transient receptor potential ankyrin 1 (TRPA1) and transient receptor potential vanilloid 1 (TRPV1) are receptors expressed in the gastrointestinal tract, but their role in gastric protection against ethanol-induced injury remains unclear. This study investigated the contribution of TRPA1 and TRPV1 to gastric responses following ethanol exposure. Wild-type mice and mice lacking

Indexed as

EthanolGastric MucosaTRPA1 Cation ChannelTRPV Cation ChannelsAnimalsMaleMiceMice, Inbred C57BLMice, KnockoutEthanolTRPA1 Cation ChannelTrpa1 protein, mouseTRPV1 protein, mouseTRPV Cation Channelsethanolgastric injuryKO animalsmucosastomachTRP receptors

Identifiers

PMID42193874
PMCPMC13204562

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.