Integrated Omics Analysis of the Effects of Nano-Antimicrobial Peptide on the Intestinal Microbiota and Metabolome of Tibetan Sheep.

Yaqin Zhao, Xiaoshan Wang, Haixia Jing, Liyuan Zhao, Fengjun Liu

Abstract read

In one paragraph

Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yaqin ZhaoDepartment of Veterinary Medicine, College of Agriculture and Animal Husbandry, Qinghai University, Xining 810016, China.

Xiaoshan WangDepartment of Veterinary Medicine, College of Agriculture and Animal Husbandry, Qinghai University, Xining 810016, China.

Haixia JingDepartment of Veterinary Medicine, College of Agriculture and Animal Husbandry, Qinghai University, Xining 810016, China.

Liyuan ZhaoQinghai Vocational and Technical Institute of Animal Husbandry and Vet, Xining 812100, China.

Fengjun LiuDepartment of Veterinary Medicine, College of Agriculture and Animal Husbandry, Qinghai University, Xining 810016, China.

Funding

Science and Technology Department of Qinghai Province 2025-NK-P58

6 · The paper itself

Abstract

This study investigated the effects of dietary nano-antimicrobial peptides (NAP) on the microbial communities and metabolic profiles in Tibetan sheep. Using 16S rRNA gene high-throughput sequencing and non-targeted metabolomics, the contents of the small intestine, rumen, and rectum were systematically analyzed in a control group (Group A) and a NAP-supplemented group (Group B). Multi-omics integration methods, including O2PLS and Pearson correlation analysis, were employed to explore the association between microbial communities and metabolites. Alpha and beta diversity analyses revealed significant differences (

Indexed as

16S rRNA genenano-antimicrobial peptidenon-targeted metabolomicsTibetan sheep

Identifiers

PMID42193834

DOI10.3390/ani16101543

PMCPMC13203225

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.