ArticleAnimals : an open access journal from MDPI2026
Insights into Canine Idiopathic Rhinitis from a Prospective Study: A Multimodal Diagnostic Perspective.
Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionIdiopathic rhinitis (IR) is one of the most common causes of chronic nasal discharge in dogs. It is a diagnosis of exclusion requiring a comprehensive diagnostic work-up to rule out other differentials. To investigate a possible allergic etiology, allergen-specific IgE antibody superclasses were evaluated.
methodsDogs with chronic nasal discharge underwent blood testing, whole-body CT, and detailed evaluation of the nasal cavity. Dogs with systemic diseases or corticosteroid treatment within two weeks prior to presentation were excluded.
resultsA total of 46 dogs were included: 13 IR, 10 malignant tumors, six benign tumors, eight other inflammatory nasal diseases, and nine controls. All IR dogs were non-brachycephalic and of various breeds. No correlation was found between sinusitis, turbinate destruction, culture-based bacteriology, or IgE positivity. A similarly high number of positive IgE results was observed across all groups. Regarding treatment and follow-up, compared to dogs with other nasal diseases, compliance among IR dog owners was comparably poor.
conclusionsAllergen-specific IgE may be elevated in dogs with IR; however, they are neither diagnostic nor predictive. As owners often perceive the disease as a harmless cold, awareness must be raised about the nasal functions in dogs and possible consequences of untreated nasal discharge.
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