ArticleBehavioral sciences (Basel, Switzerland)2026
Prenatal Alcohol Exposure Predicts Academic Outcomes from Childhood to Adolescence: A Prospective Longitudinal Study Based on Meconium Ethyl Glucuronide.
Stefan Mestermann, Maike Broich, Peter A Fasching, Matthias W Beckmann, Oliver Kratz, Jonas Hemetsberger, Maximilian Bailer, Bernd Lenz, Johannes Kornhuber, Anna Eichler and 1 more
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In one paragraphArticle in Behavioral sciences (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
11 authors.
Stefan MestermannDepartment of Child and Adolescent Mental Health, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.
Maike BroichDepartment of Child and Adolescent Mental Health, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.
Peter A FaschingDepartment of Obstetrics and Gynaecology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.ORCID 0000-0003-4885-8471 Matthias W BeckmannDepartment of Obstetrics and Gynaecology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.
Oliver KratzDepartment of Child and Adolescent Mental Health, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.
Jonas HemetsbergerDepartment of Child and Adolescent Mental Health, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.
Maximilian BailerDepartment of Psychiatry and Psychotherapy, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.ORCID 0009-0005-2506-710X Bernd LenzDepartment of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany.
Johannes KornhuberDepartment of Psychiatry and Psychotherapy, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.ORCID 0000-0002-8096-3987 Anna EichlerDepartment of Child and Adolescent Mental Health, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.ORCID 0000-0001-5584-0961 The Imac-Mind-ConsortiumUniversity Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.
Funding
Bundesministerium für Forschung, Technologie und Raumfahrt 01GL1745B, subproject TP1Else Kröner-Fresenius-Stiftung 2019_A45Universitätsbund Erlangen-Nürnberg e. V. n./a.
6 · The paper itselfAbstract
backgroundPrenatal alcohol exposure (PAE) is a major preventable cause of neurodevelopmental impairment. Little is known about its impact on real-life child/adolescent academic outcomes, which are key functional indicators of long-term social participation.
methodsPAE was assessed in a sample of 156 participants via (1) meconium ethyl glucuronide (EtG) concentration (≥10 ng/g; EtG-positive,
resultsAt t1, EtG-positive children exhibited lower school report grades by trend (
conclusionsPAE is associated with reduced real-life academic outcomes across development. School performance represents a sensitive functional outcome of neurodevelopmental vulnerability following PAE. Meconium EtG may contribute to postnatal identification of affected children.
Indexed as
academic achievementeducational trackethyl glucuronidefetal alcohol spectrum disorderneurodevelopmentperinatal periodprenatal alcohol exposureschool grades
Identifiers
PMID42193594
PMCPMC13203348
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