Evidence map›Paper›PMID 42193465›Full record

ArticleBiomedicines2026

Dissecting GPCR Contributions to Gαo-Dependent Motor Dysfunction in

Martina Di Rocco, Lorenzo Di Rienzo, Francesca Carmen Follo, Manuela D'Alessandro, Serena Galosi, Luca Pannone, Serenella Venanzi, Elia Di Schiavi, Alberto Martire, Jean-Louis Bessereau and 3 more

Abstract read
In one paragraph

Article in Biomedicines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Martina Di RoccoDepartment of Oncology and Molecular Medicine, Istituto Superiore di Sanità, 00161 Rome, Italy.
Lorenzo Di RienzoCenter for Life Nano & Neuro Science, Istituto Italiano di Tecnologia, 00161 Rome, Italy.
Francesca Carmen FolloDepartment of Oncology and Molecular Medicine, Istituto Superiore di Sanità, 00161 Rome, Italy.
Manuela D'AlessandroFaculty of Medicine and Pharmacy, University Claude Bernard Lyon 1, MeLiS, CNRS UMR5284, INSERM U1314, 69008 Lyon, France.
Serena GalosiDepartment of Human Neuroscience, Sapienza University of Rome, 00185 Rome, Italy.
Luca PannoneDepartment of Oncology and Molecular Medicine, Istituto Superiore di Sanità, 00161 Rome, Italy.ORCID 0000-0001-7027-8196
Serenella VenanziDepartment of Oncology and Molecular Medicine, Istituto Superiore di Sanità, 00161 Rome, Italy.
Elia Di SchiaviIBBR Naples Division, Institute of Biosciences and Bioresources, CNR, 80131 Naples, Italy.ORCID 0000-0002-8179-6666
Alberto MartireNational Center for Drug Research and Evaluation, Istituto Superiore di Sanità, 00161 Rome, Italy.ORCID 0000-0003-0538-4704
Jean-Louis BessereauFaculty of Medicine and Pharmacy, University Claude Bernard Lyon 1, MeLiS, CNRS UMR5284, INSERM U1314, 69008 Lyon, France.
Vincenzo LeuzziDepartment of Human Neuroscience, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-2314-6139
Edoardo MilanettiCenter for Life Nano & Neuro Science, Istituto Italiano di Tecnologia, 00161 Rome, Italy.
Simone MartinelliDepartment of Oncology and Molecular Medicine, Istituto Superiore di Sanità, 00161 Rome, Italy.ORCID 0000-0002-5843-419X

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Italian Ministry of Health, the European Union (NextGenerationEU) PNRR-MR1-2022-12376284 (CUP I83C22002690007); PNRR M6C2-Investimento 2.1 "Rafforzamento e potenziamento della ricerca biomedica del SSN"NIH HHS P40 OD010440
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Caenorhabditis elegansdrug screeninggenetic screeningGNAO1-related disordersG protein-coupled receptorsGαo signalingmovement disorders

Identifiers

PMID42193465
PMCPMC13204887

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.