Evidence map›Paper›PMID 42193248›Full record

ReviewAntioxidants (Basel, Switzerland)2026

Mega-Events, Air Pollution and Health Outcomes: A Systematic Review.

Hiba El Khattaby, Marco Panizzolo, Federica Ghelli, Samar El Sherbiny, Valeria Bellisario, Nicoletta Colombi, Roberto Bono, Giulia Squillacioti

Abstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hiba El KhattabyDepartment of Public Health and Pediatrics, University of Turin, 10126 Turin, Italy.ORCID 0009-0007-7919-1530
Marco PanizzoloDepartment of Public Health and Pediatrics, University of Turin, 10126 Turin, Italy.ORCID 0000-0003-3226-8725
Federica GhelliDepartment of Public Health and Pediatrics, University of Turin, 10126 Turin, Italy.ORCID 0000-0003-2605-3293
Samar El SherbinyDepartment of Public Health and Pediatrics, University of Turin, 10126 Turin, Italy.ORCID 0000-0002-9086-8406
Valeria BellisarioDepartment of Public Health and Pediatrics, University of Turin, 10126 Turin, Italy.ORCID 0000-0001-6286-8516
Nicoletta ColombiBiblioteca Federata di Medicina Ferdinando Rossi, University of Turin, 10126 Turin, Italy.ORCID 0000-0001-6870-5590
Roberto BonoDepartment of Public Health and Pediatrics, University of Turin, 10126 Turin, Italy.ORCID 0000-0002-2471-6594
Giulia SquillaciotiDepartment of Public Health and Pediatrics, University of Turin, 10126 Turin, Italy.ORCID 0000-0002-0655-7550

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Air pollution represents a public health threat; it is co-responsible for millions of premature deaths annually and economic losses. Mega-events create abrupt changes in air pollution providing quasi-experimental settings to investigate related health impacts. This systematic review synthesizes the evidence on air pollution level changes during mega-events and associated short-term health effects, including mortality, hospitalizations and early biological responses. A literature search was conducted in PubMed, Embase, Scopus and Web of Science up to 7 April 2025. Study quality was evaluated using the EPHPP Quality Assessment Tool for Quantitative Studies. Thirty-one studies met the inclusion criteria. Mega-events without effective air pollution control measures were associated with increased pollutant levels and higher risks of respiratory and cardiovascular morbidity. Biomarker studies demonstrated rapid and reversible changes in oxidative stress and inflammatory biomarkers in response to short-term variations in air pollution. Instead, significant reductions in air pollution during mega-events were observed upon emission control measures. The evidence is predominantly from Asian countries, no Europe/Africa studies and only one from North America, limiting generalizability. Findings indicate that mega-events may influence air quality which affects human health, reinforcing the value of temporary emission control measures strategies for future mega-events. The systematic review was registered with Prospero (CRD420251032553).

Indexed as

air pollutionbiomarkersemission control measuresfestivalshospitalizationmega-eventsmortalityOlympicsoxidative stresspublic health

Identifiers

PMID42193248
PMCPMC13203479

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.