Evidence map›Paper›PMID 42193237›Full record

ReviewAntioxidants (Basel, Switzerland)2026

Antioxidant, Anti-Inflammatory and Anticancer Peptides from Extreme Marine Environments.

Muhammad Zakariya, Eleonora Montuori, Gwendoline Kopp, Alessandro Coppola, Daniela Giordano, Stefano Bruno, Chiara Lauritano

Abstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Muhammad ZakariyaDepartment of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Via A.F. Acton 55, 80133 Napoli, Italy.ORCID 0009-0008-4971-8829
Eleonora MontuoriDepartment of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Via A.F. Acton 55, 80133 Napoli, Italy.ORCID 0000-0002-4520-5128
Gwendoline KoppDepartment of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Via A.F. Acton 55, 80133 Napoli, Italy.
Alessandro CoppolaDepartment of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Via A.F. Acton 55, 80133 Napoli, Italy.
Daniela GiordanoInstitute of Biosciences and BioResources (IBBR), National Research Council (CNR), Via Pietro Castellino 111, 80131 Napoli, Italy.ORCID 0000-0002-8891-6245
Stefano BrunoDepartment of Food and Drug, University of Parma, Area Parco delle Scienze 23/a, 43124 Parma, Italy.
Chiara LauritanoDepartment of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Via A.F. Acton 55, 80133 Napoli, Italy.ORCID 0000-0003-4580-9594

Funding

Programma Nazionale di Ricerche in Antartide PNRA18_00025
6 · The paper itself

Abstract

Marine organisms have proven to be excellent sources of bioactive natural products with potential therapeutic applications. To date, seventeen marine-derived molecules are on the market for the treatment of human diseases, mainly cancer. While multiple bioactivities of marine compounds have been consecutively reported, peptides represent promising candidates for these applications. This review focuses on peptides from marine organisms living in extreme marine environments, such as the deep ocean, polar regions, and tropical ecosystems. These are particularly promising for further bioprospecting, since their distinctive conditions have driven the evolution of unique biomolecules, as well as unique stability profile that can improve efficacy, shelf life, and performance under a wide range of industrial conditions. Ziconotide (Prialt), a neurotoxic peptide derived from the venom of a marine snail (

Indexed as

anticancercold seasdeep-seapeptidestropics

Identifiers

PMID42193237
PMCPMC13203758

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.