Evidence map›Paper›PMID 42193186›Full record

ArticleAntioxidants (Basel, Switzerland)2026

Tissue-Specific Profiles of Free and Bound Phenolics and Their In Vitro Antioxidant and Glycemic-Regulation-Related Activities in Fingered Citron (

Wenkai Guo, Guodong Zhuang, Jin Zhang, Huaming He, Yan Jia, Yongsheng Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wenkai GuoDepartment of Food Science and Engineering, Jinan University, Guangzhou 510632, China.
Guodong ZhuangDepartment of Food Science and Engineering, Jinan University, Guangzhou 510632, China.ORCID 0000-0003-4554-9323
Jin ZhangDepartment of Food Science and Engineering, Jinan University, Guangzhou 510632, China.
Huaming HeBeijing Key Laboratory of Plant Resources Research and Development, School of Light Industry Science and Engineering, Beijing Technology and Business University, Beijing 100048, China.ORCID 0000-0002-4983-7958
Yan JiaBeijing Key Laboratory of Plant Resources Research and Development, School of Light Industry Science and Engineering, Beijing Technology and Business University, Beijing 100048, China.
Yongsheng ChenDepartment of Food Science and Engineering, Jinan University, Guangzhou 510632, China.ORCID 0000-0003-0597-814X

Funding

Beijing Technology and Business University hc202204Guangdong Basic and Applied Basic Research Foundation 2026A1515011965the Project of Science and Technology of Guangzhou 2025D04J0074
6 · The paper itself

Abstract

BACKGROUND/

objectivesFingered citron (

methodsPhenolic compositions were determined by colorimetric assays and HPLC. Antioxidant activity was assessed by ORAC and PSC, and hypoglycemic-related activity by α-glucosidase and α-amylase inhibition and glucose consumption in an insulin-resistant HepG2 (IR-HepG2) cell model.

resultsPhenolic distribution followed the order peel > blend > pulp, and free > bound. HPLC identified 11 free and 5 bound phenolics, predominantly hesperidin, quercetin, and 5,7-dimethoxycoumarin. GX peel exhibited the highest free phenolic content (106.34 ± 0.23 mg GAE/100 g FW) and superior ORAC (30.56 ± 0.50 μmol TE/g FW), strongly correlating with total phenolics (

conclusionsUnder fresh-weight-based conditions, phenolic composition and in vitro bioactivities differed by fruit part, region, and phenolic fraction. Peel, especially GX peel, tended to show higher phenolic levels and stronger antioxidant-related performance, whereas the GX blend bound fraction showed the highest glucose-consumption-promoting activity.

Indexed as

antioxidant capacityfingered citronfree and bound phenolicsfunctional food ingredientsglucose consumptionIR-HepG2 cellsα-glucosidase inhibition

Identifiers

PMID42193186
PMCPMC13203400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.