Evidence map›Paper›PMID 42193074›Full record

ArticleCurrent issues in molecular biology2026

Protein NS4A of ZIKV Inhibits Glycolytic Flux by Targeting Enolase-1.

Rui Ma, Kexin Zhang, Zhengfei Qi, Lina Wang, Qingshan Bill Fu

Abstract read
In one paragraph

Article in Current issues in molecular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rui MaSchool of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Kexin ZhangSchool of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Zhengfei QiZhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan 528400, China.
Lina WangSchool of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Qingshan Bill FuSchool of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing 210023, China.ORCID 0000-0002-7445-2355

Funding

Creative Research Group of Zhongshan City Lingnan Pharmaceutical Research and Innovation team CXTD2022011National Natural Science Foundation of China 32271320
6 · The paper itself

Abstract

NS4A plays a role in forming the flavivirus replication complex, which inhibits apoptosis in host cells by inducing autophagy, thereby promoting viral replication. The host protein ENO1 interacts with NS4A, but the precise mechanism underlying this interaction and its role in viral replication remain unclear. In this study, we identified ZIKV NS4A

Indexed as

ENO1enzymatic activityglycolysisNS4AZIKV virus

Identifiers

PMID42193074
PMCPMC13204584

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.