Evidence map›Paper›PMID 42192994›Full record

ArticleCancers2026

Paquinimod Targeting of the S100A8/A9 Axis Suppresses Liver Metastasis in Aged Mice.

Takao Tsuneki, Masafumi Saito, Kimihiro Yamashita, Masayuki Ando, Keisuke Yasuda, Naoto Shirakami, Ryota Ito, Yukari Adachi, Hiroki Kagiyama, Takaaki Tachibana and 18 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Takao TsunekiDivision of Gastrointestinal Surgery, Department of Surgery, Graduate School of Medicine, Kobe University, Kobe 650-0017, Hyogo, Japan.ORCID 0000-0002-4006-8267
Masafumi SaitoDepartment of Immunology and Microbiology, National Defense Medical College, Tokorozawa 359-8513, Saitama, Japan.
Kimihiro YamashitaDivision of Gastrointestinal Surgery, Department of Surgery, Graduate School of Medicine, Kobe University, Kobe 650-0017, Hyogo, Japan.ORCID 0000-0002-4208-7138
Masayuki AndoDivision of Gastrointestinal Surgery, Department of Surgery, Graduate School of Medicine, Kobe University, Kobe 650-0017, Hyogo, Japan.
Keisuke YasudaDivision of Gastrointestinal Surgery, Department of Surgery, Graduate School of Medicine, Kobe University, Kobe 650-0017, Hyogo, Japan.
Naoto ShirakamiDivision of Gastrointestinal Surgery, Department of Surgery, Graduate School of Medicine, Kobe University, Kobe 650-0017, Hyogo, Japan.
Ryota ItoDivision of Gastrointestinal Surgery, Department of Surgery, Graduate School of Medicine, Kobe University, Kobe 650-0017, Hyogo, Japan.
Yukari AdachiDivision of Gastrointestinal Surgery, Department of Surgery, Graduate School of Medicine, Kobe University, Kobe 650-0017, Hyogo, Japan.
Hiroki KagiyamaDivision of Gastrointestinal Surgery, Department of Surgery, Graduate School of Medicine, Kobe University, Kobe 650-0017, Hyogo, Japan.
Takaaki TachibanaDivision of Gastrointestinal Surgery, Department of Surgery, Graduate School of Medicine, Kobe University, Kobe 650-0017, Hyogo, Japan.
Masaki ImaiDivision of Gastrointestinal Surgery, Department of Surgery, Graduate School of Medicine, Kobe University, Kobe 650-0017, Hyogo, Japan.
Sachiko InubushiDivision of Breast Surgery, Department of Surgery, Graduate School of Medicine, Kobe University, Kobe 650-0017, Hyogo, Japan.ORCID 0000-0003-0541-4942
Kazuki KanayamaDepartment of Biophysics, Graduate School of Health Sciences, Kobe University, Kobe 654-0142, Hyogo, Japan.ORCID 0000-0002-8981-5817
Yu-Ichiro KomaDepartment of Biophysics, Graduate School of Health Sciences, Kobe University, Kobe 654-0142, Hyogo, Japan.ORCID 0000-0002-3022-8466
Mitsugu FujitaDivision of Gastrointestinal Surgery, Department of Surgery, Graduate School of Medicine, Kobe University, Kobe 650-0017, Hyogo, Japan.ORCID 0000-0002-0000-9879
Joerg-Matthias PollokDivision of Surgery and Interventional Science, Faculty of Medical Sciences, University College London, London NW3 2QG, UK.ORCID 0000-0001-8771-4070
Yutaka SugitaDivision of Gastrointestinal Surgery, Department of Surgery, Graduate School of Medicine, Kobe University, Kobe 650-0017, Hyogo, Japan.ORCID 0000-0002-2840-1784
Taro IkedaDivision of Gastrointestinal Surgery, Department of Surgery, Graduate School of Medicine, Kobe University, Kobe 650-0017, Hyogo, Japan.
Yasufumi KoterazawaDivision of Gastrointestinal Surgery, Department of Surgery, Graduate School of Medicine, Kobe University, Kobe 650-0017, Hyogo, Japan.
Tomoaki AokiDivision of Gastrointestinal Surgery, Department of Surgery, Graduate School of Medicine, Kobe University, Kobe 650-0017, Hyogo, Japan.ORCID 0000-0002-5626-2849
Hitoshi HaradaDivision of Gastrointestinal Surgery, Department of Surgery, Graduate School of Medicine, Kobe University, Kobe 650-0017, Hyogo, Japan.
Yasunori OtowaDivision of Gastrointestinal Surgery, Department of Surgery, Graduate School of Medicine, Kobe University, Kobe 650-0017, Hyogo, Japan.ORCID 0000-0001-8421-7343
Naoki UrakawaDivision of Gastrointestinal Surgery, Department of Surgery, Graduate School of Medicine, Kobe University, Kobe 650-0017, Hyogo, Japan.ORCID 0000-0002-9154-4972
Hironobu GotoDivision of Gastrointestinal Surgery, Department of Surgery, Graduate School of Medicine, Kobe University, Kobe 650-0017, Hyogo, Japan.ORCID 0000-0002-4337-5529
Hiroshi HasegawaDivision of Gastrointestinal Surgery, Department of Surgery, Graduate School of Medicine, Kobe University, Kobe 650-0017, Hyogo, Japan.ORCID 0000-0003-1545-0509
Shingo KanajiDivision of Gastrointestinal Surgery, Department of Surgery, Graduate School of Medicine, Kobe University, Kobe 650-0017, Hyogo, Japan.
Takeru MatsudaDivision of Gastrointestinal Surgery, Department of Surgery, Graduate School of Medicine, Kobe University, Kobe 650-0017, Hyogo, Japan.
Yoshihiro KakejiDivision of Gastrointestinal Surgery, Department of Surgery, Graduate School of Medicine, Kobe University, Kobe 650-0017, Hyogo, Japan.ORCID 0000-0002-2727-0241

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

agingCD8+ T cellshepatic immune microenvironmentliver metastasismyeloid immune cellspaquinimodS100A8/A9 axis

Identifiers

PMID42192994
PMCPMC13204323

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.