Evidence map›Paper›PMID 42192940›Full record

ArticleCancers2026

Population-Level Resources and Costs Associated with Low-Risk Prostate Cancer Patients on Active Surveillance.

Soo Jin Seung, Jane Bayani, Lena Nguyen, Ning Liu, Jodi Gatley, Anisia Wong, Emilie Richard, Sarah L Barker, Anna Ying-Wah Lee, John M S Bartlett and 4 more

Abstract read
In one paragraph

Article in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Soo Jin SeungHOPE Research Centre, Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada.
Jane BayaniOntario Institute for Cancer Research, Toronto, ON M5G 0A3, Canada.
Lena NguyenInstitute for Clinical Evaluative Sciences, Toronto, ON M4N 3M5, Canada.
Ning LiuInstitute for Clinical Evaluative Sciences, Toronto, ON M4N 3M5, Canada.
Jodi GatleyInstitute for Clinical Evaluative Sciences, Toronto, ON M4N 3M5, Canada.
Anisia WongHOPE Research Centre, Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada.
Emilie RichardHOPE Research Centre, Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada.
Sarah L BarkerOntario Institute for Cancer Research, Toronto, ON M5G 0A3, Canada.
Anna Ying-Wah LeeOntario Institute for Cancer Research, Toronto, ON M5G 0A3, Canada.ORCID 0000-0001-8197-6272
John M S BartlettDepartment of Laboratory Medicine & Pathobiology, University of Edinburgh, Edinburgh EH8 9YL, UK.
David BermanDepartment of Pathology & Molecular Medicine, Queen's University, Kingston, ON K7L 3N6, Canada.
Andrew LoblawSunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada.ORCID 0000-0002-4883-1781
Craig C EarleInstitute for Clinical Evaluative Sciences, Toronto, ON M4N 3M5, Canada.
Nicole MittmannSunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada.

Funding

CIHR IGH-155179
6 · The paper itself

Abstract

backgroundThis study was conducted to evaluate the population-level healthcare resource utilization (HCRU) and costs for men diagnosed with low-risk prostate cancer (PCa) either on active surveillance (AS) or not on AS, in which AS was defined as receiving no treatment within 1 year of diagnosis and two biopsies.

methodsAS men aged 40 to 105 years, diagnosed with stage I or II PCa, had a prostate-specific antigen (PSA) level < 20 ng/mL, a Gleason score between 5 and 7, and were matched (1:1) with men not receiving AS. The index date is defined as the date 1 year after PCa diagnosis. HCRU and costs were assessed using a macro-based costing methodology and costs standardized to 2023 CAD. Means (SD) and medians (interquartile ranges) per person-year values were reported annually.

resultsDuring the year leading up to the index date, the mean number of HCRU per patient-year (PPY) was significantly lower for the AS cases versus non-AS in terms of cancer clinic visits (1.7 vs. 26.7), hospital outpatient clinic visits (3.6 vs. 4.9), all physician visits (16.3 vs. 17.5), and specialist visits (10.7 vs. 11.6). The mean overall cost PPY was $6100 ± $12,400 for AS cases and $10,400 ± $17,800 for non-AS men (median overall cost PPY= $3500 [IQR: $2100-$5700] vs. $3700 [IQR: $2100-$7200] (

conclusionsHCRU and costs calculated for AS and non-AS low-risk PCa men indicate the cost savings potential for AS.

Indexed as

active surveillancecostshealthcare resource utilizationlow-risk prostate cancerprostate cancer

Identifiers

PMID42192940
PMCPMC13204558

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.