In one paragraphArticle in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
12 authors.
Farideh Bagherzadeh-KhiabaniSchool of Public Health, University of Alberta, Edmonton, AB T6G 2R3, Canada.ORCID 0000-0003-3395-4401 Kevin R KrullDepartment of Psychology and Biobehavioral Sciences, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.ORCID 0000-0002-0476-7001 Sedigheh MirzaeiDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.ORCID 0000-0001-8240-5957 Tiange ZhengDepartment of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Jose Miguel Martinez MartinezSchool of Public Health, University of Alberta, Edmonton, AB T6G 2R3, Canada.ORCID 0000-0002-9633-1204 Kirsten K NessDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Gregory T ArmstrongDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Melissa M HudsonDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.ORCID 0000-0001-6984-2407 Leslie L RobisonDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
I-Chan HuangDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.ORCID 0000-0002-1194-3923 Funding
Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CHARLES ROBERTS · 1985 to 2026
$166.9MMach-LETSGO: Machine-LEarning of Treatment, Survey, and Genetics towards Obtaining Correct Classification of Chronic Conditions in Adult Survivors in the Childhood Cancer Survivor Study - CCSS SupplU24CA055727 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Gregory Armstrong · 1999 to 2026
$96.7MThe St. Jude Lifetime CohortU01CA195547 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI HUDSON, MELISSA M, NESS, KIRSTEN KIMBERLIE · 2015 to 2024
$14.9MPatient-Generated Health Data to Predict Childhood Cancer Survivorship OutcomesR01CA258193 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI I-Chan Huang, YUTAKA YASUI · 2021 to 2026
$3.7MPatient-Reported Outcomes Version of CTCAE involving Childhood Cancer SurvivorsR01CA238368 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI BAKER, JUSTIN N, HUANG, I-CHAN · 2019 to 2023
$3.5MLate Effects Prediction using Clinical Phenotypes and Whole Genome SequencingR01CA216354 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI YASUI, YUTAKA, ZHANG, JINGHUI · 2017 to 2021
$3.4MThe St. Jude Lifetime Cohort StudyU01CA301480 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI MELISSA M HUDSON, Kirsten Kimberlie Ness · 2025 to 2026
$2.1MSymptom progress and adverse health outcomes in adult childhood cancer survivorsR21CA202210 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI HUANG, I-CHAN, KRULL, KEVIN R · 2016 to 2017
$428kAlberta Machine Intelligence Institute 00000American Lebanese Syrian Associated Charities 00000NCI NIH HHS CA195547NCI NIH HHS CA202210NCI NIH HHS CA216354NCI NIH HHS CA21765NCI NIH HHS CA238368NCI NIH HHS CA258193NCI NIH HHS CA55727NCI NIH HHS P30 CA021765NCI NIH HHS R01 CA216354NCI NIH HHS R01 CA238368NCI NIH HHS R01 CA258193NCI NIH HHS R21 CA202210NCI NIH HHS U01 CA195547NCI NIH HHS U01 CA301480NCI NIH HHS U24 CA055727
6 · The paper itselfAbstract
backgroundAdult survivors of childhood cancer face a significant risk for treatment-related late effects that may impair health-related quality of life (HRQoL). Incorporating longitudinal changes in patient-reported symptoms beyond treatment-based risk factors may enhance the prediction of HRQoL.
methodsSurvivors (
resultsParticipants (median baseline age 26.7 years, 52% female, 90% non-Hispanic white, 41% leukemia, and 30% Hodgkin/non-Hodgkin lymphoma survivors) most frequently reported symptom domains of sensory, pain, and anxiety (50-60% at any time point), followed by depression and memory (40-50%). Consistent absence throughout follow-up was the most common pattern (41.7-98.1%), while patterns requiring symptom presence at ≥1 time point were less common (0.0-16.7%), and persistent presence throughout follow-up was rare (0.0-6.8%). Across 10 SF36-HRQoL scores, symptom-enhanced models improved prediction over non-symptom models (AUCs 0.75-0.85 vs. 0.56-0.66;
conclusionsLongitudinal symptom change patterns substantially improved future HRQoL prediction, achieving prediction accuracy that may be of clinical effectiveness. This supports regular symptom assessment and further research towards symptom-informed risk stratification in survivorship care.
Indexed as
childhood cancer survivorshealth-related quality of lifelongitudinal patternspatient-reported symptomsprediction
Identifiers
PMID42192908
PMCPMC13204071
What OpenQuestion holds
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