ArticleCancers2026
TOP2 and NOS2 Orchestrate the Generation of DNA Breaks to Promote Colitis Cancer Initiation.
Ting-Kang Chang, Shiu-Ling Li, Anne-Cécile Brunac, Jia-Jun Huang, Yen-Hsiu Yeh, Pierre Brousset, Jean-Marc Egly, Tsai-Kun Li
Abstract read
In one paragraphArticle in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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2 · The registryThe trial behind it
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5 · Who and what moneyAuthors and funding
8 authors.
Ting-Kang ChangDepartment and Graduate Institute of Microbiology, College of Medicine, National Taiwan University, No. 1 Jen-Ai Road Section 1, Taipei 10051, Taiwan.
Shiu-Ling LiDepartment and Graduate Institute of Microbiology, College of Medicine, National Taiwan University, No. 1 Jen-Ai Road Section 1, Taipei 10051, Taiwan.
Anne-Cécile BrunacDepartment of Pathology and Cytology, Institut Universitaire du Cancer de Toulouse-Oncopole, 1 Avenue Irène Joliot-Curie, 31059 Toulouse, France.ORCID 0000-0003-2741-1048 Jia-Jun HuangDepartment and Graduate Institute of Microbiology, College of Medicine, National Taiwan University, No. 1 Jen-Ai Road Section 1, Taipei 10051, Taiwan.
Yen-Hsiu YehDepartment and Graduate Institute of Microbiology, College of Medicine, National Taiwan University, No. 1 Jen-Ai Road Section 1, Taipei 10051, Taiwan.
Pierre BroussetLaboratoire d'Anatomie Cytologie Pathologiques, IUCT-Oncopole, 1 Avenue Irène Joliot-Curie, 31059 Toulouse, France.ORCID 0000-0002-8629-3291 Jean-Marc EglyDepartment of Functional Genomics and Cancer, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS/INSERM/University of Strasbourg, BP 163, Illkirch Cédex, 67404 Strasbourg, France.
Tsai-Kun LiDepartment and Graduate Institute of Microbiology, College of Medicine, National Taiwan University, No. 1 Jen-Ai Road Section 1, Taipei 10051, Taiwan.
Funding
Ministry of Science and Technology NSTC-114-2320-B-002-042, NSTC-113-2320-B-002-017, MOST 110-2634-F-002-004 and NTU-110L901401
6 · The paper itselfAbstract
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Indexed as
colitis-associated colorectal cancerDNA damage responseDNA topoisomeraseinflammationinflammatory bowel diseaseknockout micenitric oxide synthase
Identifiers
PMID42192880
PMCPMC13205054
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