ArticleCancers2026
Clinical Impact of Staple-Line Oversewing in Totally Mechanical Collard Cervical Anastomosis for Esophageal Cancer.
Article in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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9 authors.
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Abstract
backgroundCervical esophagogastric anastomosis using a gastric conduit is commonly performed after esophagectomy for esophageal cancer, but anastomotic leakage remains a major postoperative complication. Totally mechanical Collard (TMC) anastomosis provides favorable stricture outcomes; however, leakage rates remain variable. The clinical benefit of staple-line oversewing in TMC anastomosis has not been fully clarified.
methodsThis retrospective cohort study included consecutive patients who underwent esophagectomy with TMC cervical anastomosis between January 2017 and December 2024. Patients were divided into oversewing and non-oversewing groups according to whether staple-line oversewing was performed. The primary endpoint was anastomotic leakage. Secondary endpoints included leakage severity, timing of leakage onset, healing duration, anastomotic stricture, and postoperative complications. Multivariable logistic regression analysis was used to identify independent risk factors for leakage.
resultsA total of 803 patients were included (oversewing:
conclusionsStaple-line oversewing of TMC cervical anastomosis was associated with a reduced incidence and milder severity of anastomotic leakage without increasing anastomotic stricture. This simple and reproducible technique may improve anastomotic stability after esophagectomy for esophageal cancer.
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