Evidence map›Paper›PMID 42192771›Full record

ArticleBrain sciences2026

Reduced Clinical Target Volume Margins in Glioblastoma: Exploratory Evidence Supporting Further Margin Reduction Independent of MGMT Status.

Flavio Donnini, Giuseppe Minniti, Salvatore Chibbaro, Giulio Bagnacci, Armando Perrella, Giuseppe Battaglia, Giovanni Rubino, Pierpaolo Pastina, Tommaso Carfagno, Marta Vannini and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Flavio DonniniUnit of Radiation Oncology, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.ORCID 0009-0005-4084-3672
Giuseppe MinnitiRadiation Oncology, Policlinico Umberto I, Department of Radiological, Oncological and Pathological Sciences, "Sapienza" University of Rome, 00161 Rome, Italy.
Salvatore ChibbaroUnit of Neurosurgery, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.
Giulio BagnacciDiagnostic Imaging Unit, Department of Medical Sciences, Azienda Ospedaliero Universitaria Senese, 53100 Siena, Italy.
Armando PerrellaDiagnostic Imaging Unit, Department of Medical Sciences, Azienda Ospedaliero Universitaria Senese, 53100 Siena, Italy.ORCID 0000-0002-0888-5187
Giuseppe BattagliaUnit of Radiation Oncology, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.
Giovanni RubinoUnit of Radiation Oncology, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.
Pierpaolo PastinaUnit of Radiation Oncology, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.
Tommaso CarfagnoUnit of Radiation Oncology, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.
Marta VanniniUnit of Radiation Oncology, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.
Maria Antonietta MazzeiDiagnostic Imaging Unit, Department of Medical Sciences, Azienda Ospedaliero Universitaria Senese, 53100 Siena, Italy.ORCID 0000-0001-6778-6894
Alfonso CeraseDiagnostic and Therapeutic Neuroradiology Unit, University Hospital of Siena, 53100 Siena, Italy.ORCID 0000-0003-4753-6649
Paolo TiniUnit of Radiation Oncology, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.ORCID 0000-0003-4826-4809

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

clinical target volumeglioblastomamargin reductionMGMT promoter methylationprecision radiotherapyradiotherapyrecurrence patternstarget margins

Identifiers

PMID42192771
PMCPMC13204012

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.