Evidence map›Paper›PMID 42192723›Full record

ArticleAntibiotics (Basel, Switzerland)2026

Long-Term Trends in Antimicrobial Resistance Among Gram-Negative Clinical Isolates at Mubarak Al-Kabeer Hospital, Kuwait (2007-2022).

Amani H Al-Fadhli, Ahmad Al-Dhumair, Jenan AlShemerri, Fatema Al-Failakawy, Mohammad Al-Hasan, Qadreyah Ahmad Almatawah, Wafaa Y Jamal

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amani H Al-FadhliLaboratory Sciences, Department of Medical, College of Allied Health Sciences, Kuwait University, Jabriya 24923, Kuwait.ORCID 0009-0002-9826-3660
Ahmad Al-DhumairFood Security Program, Kuwait Institute for Scientific Research, Safat, Kuwait City 13109, Kuwait.ORCID 0000-0001-8905-8476
Jenan AlShemerriBarts and the London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AT, UK.
Fatema Al-FailakawyDepartment of Laboratory Medicine, Mubarak Al Kabeer Hospital, Hawally 32052, Kuwait.
Mohammad Al-HasanFood Security Program, Kuwait Institute for Scientific Research, Safat, Kuwait City 13109, Kuwait.ORCID 0000-0002-4756-7245
Qadreyah Ahmad AlmatawahFood Security Program, Kuwait Institute for Scientific Research, Safat, Kuwait City 13109, Kuwait.ORCID 0000-0002-2881-0553
Wafaa Y JamalDepartment of Microbiology, College of Medicine, Kuwait University, Jabriya 46300, Kuwait.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo examine the long-term trends in antimicrobial resistance (AMR) among major Gram-negative pathogens including

methodsThe antimicrobial resistance data for 39,200 non-duplicate Gram-negative isolates were collected from the Hospital Laboratory Information System (LIS). Retrospectively antibiotic susceptibility data were interpreted according to Clinical and Laboratory Standards Institute (CLSI) breakpoints with intermediate results classified as resistant. Logistic regression was applied to assess temporal trends in resistance for the following antibiotic cefotaxime, ceftazidime, ciprofloxacin, meropenem and imipenem. False discovery rate (FDR) correction was performed for multiple comparisons.

resultsThird-generation cephalosporin resistance increased significantly, from 27% to 60% in

conclusionsFrom 2007 to 2022, increasing resistance among major Gram-negative pathogens was observed, with cefotaxime resistance rising from 27% in 2007 to 60% in 2022 in

Indexed as

antibiotic resistanceGram-negative bacteriaKuwaitsurveillancetrends

Identifiers

PMID42192723
PMCPMC13203850

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.